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Gene · 169026

SLC30A8: solute carrier family 30 member 8

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC30A8: solute carrier family 30 member 8. Genes, record 169026. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/169026

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Gene

Symbol
SLC30A8
HGNC
Name
solute carrier family 30 member 8
HGNC
NCBI Gene ID
169026
NCBI Gene
HGNC ID
HGNC:20303
HGNC
Ensembl
ENSG00000164756
NCBI Gene
Aliases
ZNT8, ZnT-8
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8IWU4Proton-coupled zinc antiporter SLC30A83693Ensembl, GeneID, HGNC

Source UniProt

Patents77

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4698223 A22026-02-2518Q8IWU4Espacenet
JP 2026004568 A2026-01-1464441Q8IWU4Espacenet
US 12502436 B22025-12-232421Q8IWU4Espacenet
JP 2025181835 A2025-12-112421Q8IWU4Espacenet
EP 4640849 A22025-10-292489Q8IWU4Espacenet
EP 4641201 A22025-10-2916152Q8IWU4Espacenet
WO 2025199149 A12025-09-252421Q8IWU4Espacenet
JP 2025529142 A2025-09-044156Q8IWU4Espacenet
US 12371689 B22025-07-294156Q8IWU4Espacenet
JP 2025519096 A2025-06-242489Q8IWU4Espacenet

1 to 10 of 77

See all 77 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,190

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC30A8 papersNewest fiscal year
R01DK032083Multiple Autoantigens, Multiple Epitopes of Type 1 Diabetes462025
P30DK116073University of Colorado Anschutz Medical Campus DRC382025
P30DK017047Diabetes Research Center302025
P30DK020572Michigan Diabetes Research Center (MDRC)262025
P01AI042288Immune Function and the Progression to Type 1 Diabetes242025
R01DK062370Identifying Genes for Type 2 Diabetes: FUSION212025
U01DK103282Type 1 Diabetes TrialNet Clinical Network Hub212025
ZIAHG000024Genetic analysis of type II diabetes212025
P30DK045735Yale Diabetes Research Center182025
R01DK108868Insulin specific T cell response shaped by diabetes protective MHC class II molecules182025

1 to 10 of 2,190Source NIH's project files

See all 2,190 nih grants

Papers3,267

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Natural history study of type 1 diabetes risk in adults (T1DRA): protocol for screening and follow-up of UK adults.BMJ Open202642810803PubTator, text miningPubMed
Dorsal Pancreatic Agenesis Associated With New-Onset Diabetes Mellitus and Acute Pancreatitis in an 18-Year-Old Man: A Case Report.Clin Case Rep202642808003PubTator, text miningPubMed
Single Autoantibody Positivity in Pediatric Type 1 Diabetes: Serological Profiles, Clinical Trajectories and Implications for Early Disease Monitoring-A Case Series of Seven Patients.Life (Basel)202642795365PubTator, text miningPubMed
Metabolic heterogeneity at the onset of type 2 diabetes: phenotypes of insulin resistance and β-cell function in the Kazakh population.Front Endocrinol (Lausanne)202642712388PubTator, text miningPubMed
Genome-Wide Association Analyses Identify Distinct Genetic Architectures for Extreme Early-Onset and Late-Onset T2D.Diabetes Obes Metab202642712079PubTator, text miningPubMed
Berberine, a natural molecular glue degrader, overcomes CML resistance via TRIM28-mediated HIF1α ubiquitination and subsequent ferroptosis.Cell Rep202642709544PubTator, text miningPubMed
Engineering Lipid Nanoparticles through Integrated Compositional and Ligand Targeting Enhances β Cell-Directed RNA Delivery.ACS Nano202642674453PubTator, text miningPubMed
The C-terminal cysteines in zinc transporter 8 (ZnT8) form an independent epitope for autoantibody binding in newly diagnosed type 1 diabetes.Clin Exp Immunol202642671000PubTator, text miningPubMed
Double autoimmune endocrinopathies: concurrent presentation of latent autoimmune diabetes in adults and Graves disease.JCEM Case Rep202642634756PubTator, text miningPubMed
SLC30A8 (ZnT8) at the crossroads of epigenetics and microRNA regulation in type 2 diabetes and nephropathy.World J Nephrol202642626274PubTator, text miningPubMed

1 to 10 of 3,267

See all 3,267 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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