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Gene · 170302

ARX: aristaless related homeobox

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ARX: aristaless related homeobox. Genes, record 170302. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/170302

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Gene

Symbol
ARX
HGNC
Name
aristaless related homeobox
HGNC
NCBI Gene ID
170302
NCBI Gene
HGNC ID
HGNC:18060
HGNC
Ensembl
ENSG00000004848
NCBI Gene
Aliases
CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96QS3Homeobox protein ARX5620Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437842Q96QS3Espacenet
JP 2025147176 A2025-10-0614758Q96QS3Espacenet
JP 2025062604 A2025-04-146292Q96QS3Espacenet
JP 2025032204 A2025-03-1124821Q96QS3Espacenet
JP 2025028160 A2025-02-2814758Q96QS3Espacenet
KR 1020250010750 A2025-01-2114758Q96QS3Espacenet
EP 4461818 A22024-11-1324821Q96QS3Espacenet
JP 2024109657 A2024-08-1414597Q96QS3Espacenet
US 11918604 B22024-03-0512Q96QS3Espacenet
US 11918605 B12024-03-0512Q96QS3Espacenet

1 to 10 of 33

See all 33 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,070

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleARX papersNewest fiscal year
P30DK020593Vanderbilt Diabetes Research Center92025
R01NS058721ACC: Callosal Agenesis as a Window into Common Neurodevelopmental Disorders92025
P30DK019525University of Pennsylvania Diabetes Research Center82025
R01HG003988Functionally Assessing Transcriptional Enhancers In Vivo72025
P30DK050306Center for Molecular Studies in Digestive and Liver Diseases62025
R01DK090570Defining the role of MafA in islet beta cells62025
P30DK058404Molecular and Cellular Basis for Digestive Diseases52025
R01DK082590Regulation of pancreatic islet cell fate52025
R01NS029709Excitability and Plasticity of Developing Epileptic Brain52025
I01BX000666Islet alterations in type 2 diabetes42025

1 to 10 of 1,070Source NIH's project files

See all 1,070 nih grants

Papers1,566

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Comprehensive Clinicopathologic, Immunohistochemical, and Genomic Profiling of Sporadic Ampullary Somatostatin-producing D-cell Neuroendocrine Tumors Identifies Recurrent HRAS Hotspot Mutations.Endocr Pathol202642730891PubTator, text miningPubMed
Resolving human α versus β cell fate allocation for the generation of stem cell-derived islets.Nat Commun202642426000PubTator, text miningPubMed
Neuroendocrine Tumors of the Gallbladder: A Multicenter Case Series and Systematic Literature Review Indicating Predominantly Non-Aggressive Tumor Behavior and a Common Association with Cholesterol Polyps and Cholesterolosis.
Endocr Pathol202642274928PubTator, text miningPubMed
Expression of ATRX, DAXX, PDX1, ARX, and somatostatin receptors in pancreatic neuroendocrine tumors: a clinicopathological study.Front Endocrinol (Lausanne)202642199802PubTator, text miningPubMed
Robust transcriptomic signatures of Alzheimer's disease progression: validated explainable AI approach.Sci Rep202642156857PubTator, text miningPubMed
Miller-Dieker Syndrome: Genetic Etiology, Neurocognitive Impact, and Clinical Implications in a Neuronal Migration Disorder.Dev Neuropsychol202641979906PubTator, text miningPubMed
Cellular Functional Analyses of ARX Variants Reveal New Insights Into Genotype-Phenotype Correlations in Neurodevelopmental Disorders Among Male and Female Patients.Hum Mutat202641960368PubTator, text miningPubMed
Serotonin Expression and β-Cell Phenotype Are Associated With Indolent Behavior in Pancreatic Neuroendocrine Tumors With Sclerosing Morphology.J Surg Oncol202641936041PubTator, text miningPubMed
A spatiotemporal transcriptomic atlas of porcine (Sus scrofa) female early gonadal development.Commun Biol202641906042PubTator, text miningPubMed
Engineering Stem Cells for Islet Replacement Therapy: Recent Advances and Barriers for Clinical Translation.Cells202641892322PubTator, text miningPubMed

1 to 10 of 1,566

See all 1,566 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/170302

GET https://conductscience.org/api/genes/v1/170302/patents?page=2