Gene · 170482
CLEC4C: C-type lectin domain family 4 member C
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CLEC4C: C-type lectin domain family 4 member C. Genes, record 170482. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/170482
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8WTT0 | C-type lectin domain family 4 member C | 213 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents72
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026094462 A | 2026-06-09 | 29 | Q8WTT0 | Espacenet |
| EP 4705352 A1 | 2026-03-11 | 1 | Q8WTT0 | Espacenet |
| JP 2026004428 A | 2026-01-14 | 82 | Q8WTT0 | Espacenet |
| JP 2026004428 A | 2026-01-14 | 90 | Q8WTT0 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 42486 | Q8WTT0 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 42488 | Q8WTT0 | Espacenet |
| JP 2025530992 A | 2025-09-19 | 12 | Q8WTT0 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1008 | Q8WTT0 | Espacenet |
| WO 2025163564 A1 | 2025-08-07 | 82 | Q8WTT0 | Espacenet |
| WO 2025163564 A1 | 2025-08-07 | 90 | Q8WTT0 | Espacenet |
1 to 10 of 72
See all 72 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| LITIFILIMAB | CHEMBL3833308 | C-type lectin domain family 4 member C inhibitor | INHIBITOR |
Source ChEMBL
Trials7
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT06044337 | LITIFILIMAB | PHASE3 | ClinicalTrials.gov | |
| NCT05531565 | LITIFILIMAB | PHASE2/PHASE3 | ClinicalTrials.gov | |
| NCT05352919 | LITIFILIMAB | PHASE3 | ClinicalTrials.gov | |
| NCT04961567 | LITIFILIMAB | PHASE3 | ClinicalTrials.gov | |
| NCT04895241 | LITIFILIMAB | PHASE3 | ClinicalTrials.gov | |
| NCT02847598 | LITIFILIMAB | PHASE2 | 2023-05-15 | ClinicalTrials.gov |
| NCT02106897 | LITIFILIMAB | PHASE1 | ClinicalTrials.gov |
NIH grants1,584
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CLEC4C papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 8 | 2025 |
| P01CA155258 | Integrative Oncogenomics of Multiple Myeloma | 6 | 2025 |
| P30CA034196 | Cancer Center Support (CORE) Grant | 6 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 6 | 2025 |
| R01AR071384 | Characterization of interferon kappa as a novel target in cutaneous lupus | 6 | 2025 |
| U19AI057229 | Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro | 6 | 2025 |
| K24AR076975 | Linking Disease Mechanisms and Outcomes in Rheumatic Diseases | 5 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 5 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,584Source NIH's project files
See all 1,584 nih grantsPapers2,250
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Stress-driven reprogramming of plasmacytoid dendritic cells in intrahepatic cholangiocarcinoma defines a reversible targetable immunosuppressive state. | World J Surg Oncol | 2026 | 42760567 | PubTator, text mining | PubMed |
| Endoplasmic reticulum stress promotes leukemic plasmacytoid dendritic cell differentiation skewing and immune suppression in acute myeloid leukemia. | Leukemia | 2026 | 42547819 | PubTator, text mining | PubMed |
| Targeted therapies against type I interferon and TNF-alpha in cutaneous lupus erythematosus: A systematic review of randomized trials. | Dermatol Online J | 2026 | 42522516 | PubTator, text mining | PubMed |
| Clonal lineage tracing of innate immune cells in human cancer. | Cancer Cell | 2026 | 42242233 | PubTator, text mining | PubMed |
| Paradoxical Expression of Ionotropic Glutamate Receptors in Leucocytes. | Clin Rev Allergy Immunol | 2026 | 41854785 | PubTator, text mining | PubMed |
| Integrating interferon gamma receptor pathways, antigenicity, and immune contexture as predictors of immunotherapeutic strategies for mucosal melanomas. | J Immunother Cancer | 2026 | 41791790 | PubTator, text mining | PubMed |
| BDCA2 plays a central role in the binding, internalization and response of plasmacytoid dendritic cells to vidutolimod. | Front Immunol | 2026 | 41777892 | PubTator, text mining | PubMed |
| Uncovering potential molecular biomarkers for cancer-associated secondary lymphedema through integrated analyses of RNA-sequencing, machine learning, and clinical data. | Front Oncol | 2026 | 41768256 | PubTator, text mining | PubMed |
| Distinguishing post-COVID from long-COVID in adults: Development and validation of a biomarker signature using targeted proteomics and machine learning in a cross-sectional observational study. | PLoS One | 2026 | 41758880 | PubTator, text mining | PubMed |
| Single-cell dissection of hepatocellular carcinoma immunity: from heterogeneous subtypes to precision therapeutics. | Front Immunol | 2026 | 41756301 | PubTator, text mining | PubMed |
1 to 10 of 2,250
See all 2,250 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/170482
GET https://conductscience.org/api/genes/v1/170482/patents?page=2