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Gene · 170482

CLEC4C: C-type lectin domain family 4 member C

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CLEC4C: C-type lectin domain family 4 member C. Genes, record 170482. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/170482

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Gene

Symbol
CLEC4C
HGNC
Name
C-type lectin domain family 4 member C
HGNC
NCBI Gene ID
170482
NCBI Gene
HGNC ID
HGNC:13258
HGNC
Ensembl
ENSG00000198178
NCBI Gene
Aliases
BDCA-2, BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, PRO34150
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8WTT0C-type lectin domain family 4 member C2135Ensembl, GeneID, HGNC

Source UniProt

Patents72

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026094462 A2026-06-0929Q8WTT0Espacenet
EP 4705352 A12026-03-111Q8WTT0Espacenet
JP 2026004428 A2026-01-1482Q8WTT0Espacenet
JP 2026004428 A2026-01-1490Q8WTT0Espacenet
JP 2026004568 A2026-01-1442486Q8WTT0Espacenet
JP 2026004568 A2026-01-1442488Q8WTT0Espacenet
JP 2025530992 A2025-09-1912Q8WTT0Espacenet
JP 2025529142 A2025-09-041008Q8WTT0Espacenet
WO 2025163564 A12025-08-0782Q8WTT0Espacenet
WO 2025163564 A12025-08-0790Q8WTT0Espacenet

1 to 10 of 72

See all 72 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
LITIFILIMABCHEMBL3833308C-type lectin domain family 4 member C inhibitorINHIBITOR

Source ChEMBL

Trials7

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06044337LITIFILIMABPHASE3ClinicalTrials.gov
NCT05531565LITIFILIMABPHASE2/PHASE3ClinicalTrials.gov
NCT05352919LITIFILIMABPHASE3ClinicalTrials.gov
NCT04961567LITIFILIMABPHASE3ClinicalTrials.gov
NCT04895241LITIFILIMABPHASE3ClinicalTrials.gov
NCT02847598LITIFILIMABPHASE22023-05-15ClinicalTrials.gov
NCT02106897LITIFILIMABPHASE1ClinicalTrials.gov

NIH grants1,584

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCLEC4C papersNewest fiscal year
P30CA016672Cancer Center Support Grant142025
P30CA008748Cancer Center Support Grant82025
P01CA155258Integrative Oncogenomics of Multiple Myeloma62025
P30CA034196Cancer Center Support (CORE) Grant62025
P30CA091842Cancer Center Support Grant62025
R01AR071384Characterization of interferon kappa as a novel target in cutaneous lupus62025
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro62025
K24AR076975Linking Disease Mechanisms and Outcomes in Rheumatic Diseases52025
P30AI027763UCSF-Bay Area Center for AIDS Research52025
P30CA016042Cancer Center Support Grant52025

1 to 10 of 1,584Source NIH's project files

See all 1,584 nih grants

Papers2,250

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Stress-driven reprogramming of plasmacytoid dendritic cells in intrahepatic cholangiocarcinoma defines a reversible targetable immunosuppressive state.World J Surg Oncol202642760567PubTator, text miningPubMed
Endoplasmic reticulum stress promotes leukemic plasmacytoid dendritic cell differentiation skewing and immune suppression in acute myeloid leukemia.Leukemia202642547819PubTator, text miningPubMed
Targeted therapies against type I interferon and TNF-alpha in cutaneous lupus erythematosus: A systematic review of randomized trials.Dermatol Online J202642522516PubTator, text miningPubMed
Clonal lineage tracing of innate immune cells in human cancer.Cancer Cell202642242233PubTator, text miningPubMed
Paradoxical Expression of Ionotropic Glutamate Receptors in Leucocytes.Clin Rev Allergy Immunol202641854785PubTator, text miningPubMed
Integrating interferon gamma receptor pathways, antigenicity, and immune contexture as predictors of immunotherapeutic strategies for mucosal melanomas.J Immunother Cancer202641791790PubTator, text miningPubMed
BDCA2 plays a central role in the binding, internalization and response of plasmacytoid dendritic cells to vidutolimod.Front Immunol202641777892PubTator, text miningPubMed
Uncovering potential molecular biomarkers for cancer-associated secondary lymphedema through integrated analyses of RNA-sequencing, machine learning, and clinical data.Front Oncol202641768256PubTator, text miningPubMed
Distinguishing post-COVID from long-COVID in adults: Development and validation of a biomarker signature using targeted proteomics and machine learning in a cross-sectional observational study.PLoS One202641758880PubTator, text miningPubMed
Single-cell dissection of hepatocellular carcinoma immunity: from heterogeneous subtypes to precision therapeutics.Front Immunol202641756301PubTator, text miningPubMed

1 to 10 of 2,250

See all 2,250 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/170482

GET https://conductscience.org/api/genes/v1/170482/patents?page=2