Gene · 1717
DHCR7: 7-dehydrocholesterol reductase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DHCR7: 7-dehydrocholesterol reductase. Genes, record 1717. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1717
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UBM7 | 7-dehydrocholesterol reductase | 475 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents52
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 387 | Q9UBM7 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 35856 | Q9UBM7 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 35857 | Q9UBM7 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7181 | Q9UBM7 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 1055 | Q9UBM7 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 7098 | Q9UBM7 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 390 | Q9UBM7 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1255 | Q9UBM7 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1255 | Q9UBM7 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 1055 | Q9UBM7 | Espacenet |
1 to 10 of 52
See all 52 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,599
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DHCR7 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 8 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 8 | 2025 |
| P30ES005605 | Environmental Health Sciences Research Center | 5 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 4 | 2025 |
| P30CA043703 | Case Comprehensive Cancer Center Support Grant | 4 | 2025 |
| P30ES007033 | University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment | 4 | 2025 |
| P50AA011999 | Southern California Research Center for ALPD and Cirrhosis | 4 | 2025 |
| R01AR073004 | Mechanism of action and function of novel secosteroid 20(OH)D3 in the skin | 4 | 2025 |
| U01CA167552 | Cancer Epidemiology Cohort in Male Health Professionals | 4 | 2025 |
| UL1TR001881 | UCLA Clinical and Translational Science Institute | 4 | 2025 |
1 to 10 of 1,599Source NIH's project files
See all 1,599 nih grantsPapers2,258
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Environmental endocrine disruptors activate CBX2 to disrupt cholesterol homeostasis in PCOS. | J Steroid Biochem Mol Biol | 2027 | 42628813 | PubTator, text mining | PubMed |
| Human-biased MEIS1 expression by a promoter noncoding RNA regulates neural stem cell proliferation. | Life Sci Alliance | 2026 | 42816420 | PubTator, text mining | PubMed |
| The Role of Vitamin D in Noninfectious Uveitis: A Scoping Review with Transcriptomic and Bioinformatic Insights. | Ocul Immunol Inflamm | 2026 | 42784771 | PubTator, text mining | PubMed |
| Characterizing features of the genetic architecture underlying autism from a multi-ancestry perspective. | Mol Psychiatry | 2026 | 42728317 | PubTator, text mining | PubMed |
| The dual nature of 7-Dehydrocholesterol: Implications for ferroptosis, oxidative stress, and disease therapy. | Free Radic Biol Med | 2026 | 42727831 | PubTator, text mining | PubMed |
| Brusatol Triggers Cell Cycle Arrest and Apoptosis, Disrupts Sterol Biosynthesis, and Enhances the Anti-Leukemic Activity of Venetoclax in AML Cells. | Cell Biochem Biophys | 2026 | 42711651 | PubTator, text mining | PubMed |
| CAFs-mediated histone lactylation reprograms cholesterol metabolism in colorectal cancer to drive CD8+ T cell immunosuppression. | J Pathol | 2026 | 42711289 | PubTator, text mining | PubMed |
| A Potential Link Between Dyslipidemia and Inflammation in Patients with Schizophrenia: Insights from Sterols and HDL Profile Analysis. | Int J Mol Sci | 2026 | 42653224 | PubTator, text mining | PubMed |
| 7-Dehydrocholesterol-mediated ferroptosis is governed by glucose availability in pancreatic ductal adenocarcinoma. | Acta Biochim Biophys Sin (Shanghai) | 2026 | 42584968 | PubTator, text mining | PubMed |
| Genetic determinants of response to vitamin D supplementation. | Front Nutr | 2026 | 42528639 | PubTator, text mining | PubMed |
1 to 10 of 2,258
See all 2,258 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1717
GET https://conductscience.org/api/genes/v1/1717/patents?page=2