Gene · 1746
DLX2: distal-less homeobox 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DLX2: distal-less homeobox 2. Genes, record 1746. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1746
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q07687 | Homeobox protein DLX-2 | 328 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents41
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 44037 | Q07687 | Espacenet |
| JP 2025184866 A | 2025-12-18 | 11 | Q07687 | Espacenet |
| JP 2025184867 A | 2025-12-18 | 11 | Q07687 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 14871 | Q07687 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 14871 | Q07687 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 14871 | Q07687 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14710 | Q07687 | Espacenet |
| US 11998540 B2 | 2024-06-04 | 1 | Q07687 | Espacenet |
| JP 2023543360 A | 2023-10-13 | 21 | Q07687 | Espacenet |
| JP 2023543361 A | 2023-10-13 | 28 | Q07687 | Espacenet |
1 to 10 of 41
See all 41 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,283
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DLX2 papers | Newest fiscal year |
|---|---|---|---|
| R01HG003988 | Functionally Assessing Transcriptional Enhancers In Vivo | 6 | 2025 |
| T32HD007470 | Predoctoral Training in Developmental Biology | 6 | 2025 |
| I01BX000252 | Chromatin-based regulation of neural stem cells | 5 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 4 | 2025 |
| R01AA023797 | Cellular and genomic mechanisms of the impact of ethanol on human neural model | 4 | 2025 |
| R01MH106575 | Systematic Functional Interpretation of Regulatory Variants in Neuropsychiatric Disorders | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P50CA116201 | Mayo Clinic Breast Cancer SPORE | 3 | 2025 |
| R01CA228700 | Epstein-Barr virus LMP1 mediated oncogenicity | 3 | 2025 |
| R01MH124808 | Genomic and functional characterization of ASD and ID-associated MYT1L mutation | 3 | 2025 |
1 to 10 of 1,283Source NIH's project files
See all 1,283 nih grantsPapers1,337
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| TESERA: Morphologic subtyping and prognostic stratification of hepatocellular carcinoma from H&E whole-slide images. | Hepatology | 2026 | 42826064 | PubTator, text mining | PubMed |
| Directing GABAergic neuronal identity from human iPSCs through developmental patterning. | Stem Cell Reports | 2026 | 42785309 | PubTator, text mining | PubMed |
| The DLX/Notch axis is necessary for spatiotemporal regulation of neural cell fate. | Nat Commun | 2026 | 42754574 | PubTator, text mining | PubMed |
| Generation of GABAergic Neurons from Human Induced Pluripotent Stem Cells Using Doxycycline-Inducible ASCL1/DLX2 Expression at AAVS1. | J Vis Exp | 2026 | 42612101 | PubTator, text mining | PubMed |
| rs2357322 and rs17726078 Contribute to Breast Cancer Risk by Regulating DLX2 Expression. | Breast J | 2026 | 42596720 | PubTator, text mining | PubMed |
| PTTG1-DLX2 axis drives malignant progression of lung adenocarcinoma by activating the WNT/β-catenin signaling pathway. | Transl Cancer Res | 2026 | 42180979 | PubTator, text mining | PubMed |
| Single-cell multi-omics analysis reveals two molecular subtypes of human male breast cancer with distinct neuroendocrine and immune characteristics. | J Adv Res | 2026 | 42144060 | PubTator, text mining | PubMed |
| CRISPR Screens Reveal Epstein-Barr Virus-activated JunB as a Key Lymphoblastoid B cell Dependency Factor that Represses Cyclin Dependent Kinase Inhibitor P18INK4c. | bioRxiv | 2026 | 41959378 | PubTator, text mining | PubMed |
| Stress-relaxing granular bioprinting materials enable complex and uniform organoid self-organization. | Nat Mater | 2026 | 41807773 | PubTator, text mining | PubMed |
| Exploring roles of neuroglobin in oxygen homeostasis and neurodevelopment based on human cerebral organoid models. | iScience | 2026 | 41797899 | PubTator, text mining | PubMed |
1 to 10 of 1,337
See all 1,337 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1746
GET https://conductscience.org/api/genes/v1/1746/patents?page=2