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Gene · 1758

DMP1: dentin matrix acidic phosphoprotein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DMP1: dentin matrix acidic phosphoprotein 1. Genes, record 1758. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1758

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Gene

Symbol
DMP1
HGNC
Name
dentin matrix acidic phosphoprotein 1
HGNC
NCBI Gene ID
1758
NCBI Gene
HGNC ID
HGNC:2932
HGNC
Ensembl
ENSG00000152592
NCBI Gene
Aliases
ARHP, ARHR, DMP-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13316Dentin matrix acidic phosphoprotein 15130Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1443595Q13316Espacenet
EP 4650780 A22025-11-196595Q13316Espacenet
EP 4641201 A22025-10-296344Q13316Espacenet
JP 2025147176 A2025-10-064338Q13316Espacenet
JP 2025529142 A2025-09-046192Q13316Espacenet
US 12371689 B22025-07-296192Q13316Espacenet
JP 2025517969 A2025-06-126344Q13316Espacenet
JP 2025517970 A2025-06-126595Q13316Espacenet
JP 2025032204 A2025-03-1127349Q13316Espacenet
JP 2025028160 A2025-02-284338Q13316Espacenet

1 to 10 of 33

See all 33 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants914

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDMP1 papersNewest fiscal year
R01DE019802DSPP signaling in dentinogenesis92025
P30CA012197Cancer Center Support Grant62025
R01AR053237Lrp5 and Lrp6 signaling in bone mechanotransduction and metabolism62025
R01DE029816Role of complement receptor C5L2 in reparative dentinogenesis62025
P20GM125503Center for Musculoskeletal Disease Research (CMDR)52025
R01AR049794Osteocyte Control of Bone Remodeling52025
UL1TR001863Yale Clinical and Translational Science Award52025
ZIADE000649Skeletal Disorders and Mineral Homeostasis Section52025
P30CA008748Cancer Center Support Grant42025
R01DE031737Role of DMP1 Mediated Paracrine Signaling in Vasculogenesis42025

1 to 10 of 914Source NIH's project files

See all 914 nih grants

Papers2,543

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
miR-1246 regulates odontogenic differentiation of human dental pulp stem cells in an inflammatory microenvironment by targeting AXIN2: an in vitro study.Acta Odontol Scand202642752890PubTator, text miningPubMed
A bone fragment-based protocol for RNA analysis of osteocyte-associated transcripts in surgically obtained human bone specimens.MethodsX202642733764PubTator, text miningPubMed
Combined Cannabidiol and Δ9-Tetrahydrocannabinol Modulate Inflammation and Nociceptive Signaling in Human Dental Pulp Cells.J Endod202642722230PubTator, text miningPubMed
Effects of High-Calcium/Phosphorus Bioactive Glass on Human Dental Pulp Stem Cells and Interfacial Reactivity Observed by 31P Nuclear Magnetic Resonance.Int Dent J202642721693PubTator, text miningPubMed
PLXDC2-OT-peptide Promotes the Odontogenic/Osteogenic Differentiation of SCAPs via the PI3K-AKT Signalling Pathway.Int Dent J202642721690PubTator, text miningPubMed
Astragalus polysaccharide attenuates inflammation and restores odontogenic/osteogenic differentiation of hDPSCs.Arch Oral Biol202642691951PubTator, text miningPubMed
Optogenetic control of odontoblastic differentiation in dental pulp stem cells (DPSC).J Dent Sci202642689111PubTator, text miningPubMed
Molecular Cues from Extracellular Matrix Proteins Drive the Differentiation of Dental Pulp Stem Cells into Endothelial Cells in the Presence of Dentin Matrix Protein 1.J Endod202642628728PubTator, text miningPubMed
Mechanical loading under estrogen deficiency enhances mineralization and osteoblast maturation in an advanced 3D vascularized bone organoid driven by hypertrophy and apoptosis.J Biomech202642617537PubTator, text miningPubMed
FOXO3a promotes odontoblast differentiation in human dental pulp cells in coordination with RUNX2.J Appl Oral Sci202642615782PubTator, text miningPubMed

1 to 10 of 2,543

See all 2,543 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1758

GET https://conductscience.org/api/genes/v1/1758/patents?page=2