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Gene · 1759

DNM1: dynamin 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DNM1: dynamin 1. Genes, record 1759. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1759

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Gene

Symbol
DNM1
HGNC
Name
dynamin 1
HGNC
NCBI Gene ID
1759
NCBI Gene
HGNC ID
HGNC:2972
HGNC
Ensembl
ENSG00000106976
NCBI Gene
Aliases
DEE31, DEE31A, DEE31B, DNM, EIEE31
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q05193Dynamin-186422Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444405Q05193Espacenet
EP 4641201 A22025-10-299438Q05193Espacenet
JP 2025532779 A2025-10-031Q05193Espacenet
JP 2025517969 A2025-06-129438Q05193Espacenet
WO 2024058196 A2024-03-211Q05193Espacenet
JP 2023551068 A2023-12-06231Q05193Espacenet
US 11446398 B22022-09-2025936Q05193Espacenet
US 11371991 B22022-06-2819Q05193Espacenet
JP 2022524081 A2022-04-27128907Q05193Espacenet
US 10725035 B22020-07-2819Q05193Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,568

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDNM1 papersNewest fiscal year
P30DA018343Yale/NIDA Neuroproteomics Center112025
ZIADK060100Structure And Function Of Dynamin, A 100kd GTPase Involved In Endocytosis112025
ZIANS003123Role of mitochondria in neurodegenerative diseases82025
P30DK045735Yale Diabetes Research Center62025
R01AA012404Gene Expression in the Human Alcoholic Brain62025
R28AA012725Brain Tissue Resource Center for Alcohol Research52025
R01MH101221Rare Mutations and Autism Spectrum Disorders42025
R01NS031348Genetic Determinants of Epilepsy in Murine Systems42025
R01NS102722Endosomal Platforms for Signaling Pain42025
U01AA0209262/11 Spatially Resolved, Single Cell, Neuroimmune Transcriptomes in Alcohol Dependence42025

1 to 10 of 1,568Source NIH's project files

See all 1,568 nih grants

Papers1,884

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Patient-Derived Organoids as a Model to Understand Tumor Microenvironment-Driven Nano-Bio Interactions - A Framework Towards Improved Nanomedicine Translation.bioRxiv202642818659PubTator, text miningPubMed
Ambrisentan rescues doxorubicin-induced cardiac apoptosis and mitochondrial bioenergetic dysfunction: Mechanistic insights into p53 and mTOR signaling.Biochem Pharmacol202642727655PubTator, text miningPubMed
High-fat diet-responsive DNM1 promotes hepatocellular carcinoma progression and predicts poor prognosis in viral-associated patients.Am J Cancer Res202642724488PubTator, text miningPubMed
Female chronic social defeat stress (femCSDS) maps synaptic, bioenergetic and metabolic proteome remodeling in the nucleus accumbens (NAc).Front Syst Biol202642614171PubTator, text miningPubMed
Large-scale whole-genome sequencing reveals the landscape and health implications of de novo mutations.Nat Med202642567929PubTator, text miningPubMed
Inhibition of ETS1/DRP1 axis attenuates intervertebral disc degeneration by suppressing excessive mitochondrial fission.Cell Signal202642526698PubTator, text miningPubMed
Targeting Synaptic Vesicle Endocytosis in Nociceptors Provides Sustained Pain Relief.bioRxiv202642395445PubTator, text miningPubMed
Refining Domain-Based Prognostication in DNM1 Encephalopathy: A Mild Phenotype Associated With a GTPase Domain Variant.Am J Med Genet A202642286426PubTator, text miningPubMed
Dapagliflozin Protects Cardiomyocytes against Doxorubicin-Induced Toxicity by Modulating Sirtuin 1/Sirtuin 3 and Ferroptosis Pathway.ACS Pharmacol Transl Sci202642130718PubTator, text miningPubMed
Modeling Synaptic Maturation From Growth Cone to Synapse in Human Organoids.J Neurochem202642108706PubTator, text miningPubMed

1 to 10 of 1,884

See all 1,884 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1759

GET https://conductscience.org/api/genes/v1/1759/patents?page=2