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ACAN: aggrecan

1 protein, 44 patents, 0 drugs, 0 trials, 3,800 NIH grants and 12,645 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolACANHGNC
NameaggrecanHGNC
NCBI Gene ID176NCBI Gene
HGNC IDHGNC:319HGNC
EnsemblENSG00000157766NCBI Gene
AliasesAGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK, SSOAODNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P16112Aggrecan core protein2,5304Ensembl, GeneID, HGNCUniProt

Patents 44

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026510738 A2026-04-108P16112Espacenet
EP 4676555 A12026-01-148P16112Espacenet
JP 2026004568 A2026-01-1436939P16112Espacenet
JP 2026004568 A2026-01-1436941P16112Espacenet
EP 4650780 A22025-11-1912161P16112Espacenet
EP 4641201 A22025-10-2913165P16112Espacenet
JP 2025147176 A2025-10-06102P16112Espacenet
JP 2025147176 A2025-10-06105P16112Espacenet
JP 2025517969 A2025-06-1213165P16112Espacenet
JP 2025517970 A2025-06-1212161P16112Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3800

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30AG028716Duke Claude D. Pepper Older Americans Independence Center232,025NIH's project files
P30AR069619Overall: Resource-based Center for Musculoskeletal Disorders Research (Overall Application)222,025NIH's project files
P30AG024827Pittsburgh Older Americans Independence Center172,025NIH's project files
P30AR074992RESOURCE BASED CENTER FOR MUSCULOSKELETAL BIOLOGY AND MEDICINE122,025NIH's project files
R01AG044034Oxidative Stress and the Development of Osteoarthritis112,025NIH's project files
T32AR060719Skeletal Disorders Training Program112,025NIH's project files
ZIAHD000640Regulation Of Childhood Growth112,025NIH's project files
P41EB021911Center for Modular Manufacturing of Structural Tissues102,025NIH's project files
P30AR073752Washington University Rheumatic Diseases Research Resource-based Center92,025NIH's project files
T32AR007132Training Program in Musculoskeletal Research92,025NIH's project files

Papers 12645

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827044PubTator, text miningPubMed
42824949PubTator, text miningPubMed
42821015PubTator, text miningPubMed
42812603PubTator, text miningPubMed
42809989PubTator, text miningPubMed
42801603PubTator, text miningPubMed
42800420PubTator, text miningPubMed
42792769PubTator, text miningPubMed
42783699PubTator, text miningPubMed
42778025PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license