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Gene · 1760

DMPK: DM1 protein kinase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DMPK: DM1 protein kinase. Genes, record 1760. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1760

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Gene

Symbol
DMPK
HGNC
Name
DM1 protein kinase
HGNC
NCBI Gene ID
1760
NCBI Gene
HGNC ID
HGNC:2933
HGNC
Ensembl
ENSG00000104936
NCBI Gene
Aliases
DM, DM1, DM1PK, DMK, MDPK, MT-PK
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q09013Myotonin-protein kinase6292Ensembl, GeneID, HGNC

Source UniProt

Patents22

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444581Q09013Espacenet
JP 2025166094 A2025-11-052Q09013Espacenet
JP 2025529142 A2025-09-041276Q09013Espacenet
US 12371689 B22025-07-291276Q09013Espacenet
JP 2024105681 A2024-08-062Q09013Espacenet
US 11446398 B22022-09-2026340Q09013Espacenet
JP 2022524081 A2022-04-27129311Q09013Espacenet
JP 2021534755 A2021-12-1672Q09013Espacenet
EP 3841209 A12021-06-302Q09013Espacenet
WO 2020043864 A12020-03-05703Q09013Espacenet

1 to 10 of 22

See all 22 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,542

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDMPK papersNewest fiscal year
R01NS098819Molecular effects of metformin, PKR and TBI on C9orf72 ALS/FTD132025
P30CA016672Cancer Center Support Grant82025
R01MH062646Regulation of Signaling by mGluR582025
R35NS116846Design of Precision Small Molecules Targeting RNA Repeating Transcripts to Manipulate and Study Disease Biology82025
ZIACP010144Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes82025
R35GM118103Recognition of Cellular Targets by single and double-stranded nucleic acids72025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant62025
R01NS031373Functions of Metabotropic Glutamate Receptor Subtypes62025
R01NS103172Therapeutic strategies for microsatellite expansion diseases using RNA targeting62025
P30EY030413Core Grant for Vision Research52025

1 to 10 of 1,542Source NIH's project files

See all 1,542 nih grants

Papers3,275

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Disruption of RNA metabolism and its impact on protein homeostasis.Philos Trans R Soc Lond B Biol Sci202642817623PubTator, text miningPubMed
Antisense Oligonucleotide-Mediated Degradation of Toxic RNA in Myotonic Dystrophy Type 1.Methods Mol Biol202642814302PubTator, text miningPubMed
MBNL depletion drives stem cell fusion and immature myonuclear states in myotonic dystrophy type 1.Nat Commun202642693134PubTator, text miningPubMed
CRISPR/dCas9-mediated tuning of DMPK transcription reveals a quantitative relationship between toxic repeat RNA expression and MBNL1 activity in myotonic dystrophy.Hum Mol Genet202642627995PubTator, text miningPubMed
An Ultrastructural and Proteomic Analysis in DM1 Young Adults' Myoblasts: Stressed RER and Mitochondrial Dysfunction Involvement.J Cell Mol Med202642601835PubTator, text miningPubMed
Prenatal manifestations and perinatal outcomes in congenital myotonic dystrophy: clinical patterns and diagnostic implications.Case Rep Perinat Med202642577704PubTator, text miningPubMed
Natural History of Adult-Onset Myotonic Dystrophy Type 1: Longitudinal Changes in Radiologic, Clinical, and Patient-Reported Outcomes.Neurology202642525903PubTator, text miningPubMed
Genotype-phenotype relationship in a cohort of 131 Chinese patients with myotonic dystrophy type 1.BMC Neurol202642471599PubTator, text miningPubMed
Atypical Phenotype of Myotonic Dystrophy Type 1 with Variant Repeats at the Age of Diagnosis.Biology (Basel)202642450630PubTator, text miningPubMed
Aberrant neuronal differentiation and splicing defects in Congenital Myotonic Dystrophy (DM1) iPSC models.bioRxiv202642427665PubTator, text miningPubMed

1 to 10 of 3,275

See all 3,275 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1760

GET https://conductscience.org/api/genes/v1/1760/patents?page=2