ConductScience.org, home

Gene · 1761

DMRT1: doublesex and mab-3 related transcription factor 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. DMRT1: doublesex and mab-3 related transcription factor 1. Genes, record 1761. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1761

On this page

Gene

Symbol
DMRT1
HGNC
Name
doublesex and mab-3 related transcription factor 1
HGNC
NCBI Gene ID
1761
NCBI Gene
HGNC ID
HGNC:2934
HGNC
Ensembl
ENSG00000137090
NCBI Gene
Aliases
CT154, DMT1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y5R6Doublesex- and mab-3-related transcription factor 13731Ensembl, GeneID, HGNC

Source UniProt

Patents17

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444243Q9Y5R6Espacenet
JP 2025147176 A2025-10-0614878Q9Y5R6Espacenet
JP 2025028160 A2025-02-2814878Q9Y5R6Espacenet
KR 1020250010750 A2025-01-2114878Q9Y5R6Espacenet
JP 2024109657 A2024-08-1414717Q9Y5R6Espacenet
US 11446398 B22022-09-2025540Q9Y5R6Espacenet
JP 2022524081 A2022-04-27128511Q9Y5R6Espacenet
JP 2021536249 A2021-12-2715071Q9Y5R6Espacenet
US 11078247 B22021-08-033124Q9Y5R6Espacenet
JP 2021507703 A2021-02-2515031Q9Y5R6Espacenet

1 to 10 of 17

See all 17 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants606

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDMRT1 papersNewest fiscal year
R01HD078641Genomics of spermatogenic impairment92025
P30CA042014Cancer Center Support Grant52025
ZIACP010144Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes52025
ZIAHD001602Regulation Of Intracellular Iron Metabolism52025
P30CA016520Abramson Cancer Center Support Grant42025
P50HD103525WASHINGTON UNIVERSITY INTELLECTUAL AND DEVELOPMENTAL DISABILITIES RESEARCH CENTER42025
P30ES013508Center of Excellence in Environmental Toxicology32025
P50HD096723Genetics of Male Infertility: Accelerating the pace of discovery32025
R01ES007331Mechanisms of Methylmercury Induced Neuronal Toxicity32025
R01ES010563Mechanisms of Manganese Neurotoxicity32025

1 to 10 of 606Source NIH's project files

See all 606 nih grants

Papers1,350

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Gestational Changes in Placental Iron Homeostasis are Associated With Ferroptosis-Associated Redox Signaling and Trophoblast Behavior.FASEB J202642803694PubTator, text miningPubMed
Initial perturbations triggered by p53 loss in stem cells.Genes Dev202642772962PubTator, text miningPubMed
Lysosome DMT1-Mediated Renal Cell Ferroptosis Induced by Ochratoxin A.J Agric Food Chem202642677654PubTator, text miningPubMed
Spermatocytic tumours containing an intratubular component: a multi-institutional study emphasizing diagnostic pitfall with germ cell neoplasia in situ.Histopathology202642596731PubTator, text miningPubMed
Identification of genetic markers of quinine partial resistance in Plasmodium falciparum.Nat Microbiol202642410209PubTator, text miningPubMed
Nano-Selenium Alleviates Heat Stress-Induced Testicular Injury in Roosters via Inhibiting Ferroptosis.J Agric Food Chem202642381562PubTator, text miningPubMed
Multi-elemental fingerprinting of the human brain: distribution of toxic, essential, and rare earth elements across neocortical, limbic, and subcortical regions.Sci Rep202642225853PubTator, text miningPubMed
MiR-940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes.Adv Sci (Weinh)202642212965PubTator, text miningPubMed
A duplicated female pathway gene figla-like evolves as the male sex-determining gene in tilapia.J Genet Genomics202642140582PubTator, text miningPubMed
Ultrafine particles induce ferroptosis-like stress features in human dopaminergic LUHMES cells via the p53/xCT/GSH/cGPx4 axis.Toxicol In Vitro202642102973PubTator, text miningPubMed

1 to 10 of 1,350

See all 1,350 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1761

GET https://conductscience.org/api/genes/v1/1761/patents