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Gene · 1785

DNM2: dynamin 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DNM2: dynamin 2. Genes, record 1785. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1785

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Gene

Symbol
DNM2
HGNC
Name
dynamin 2
HGNC
NCBI Gene ID
1785
NCBI Gene
HGNC ID
HGNC:2974
HGNC
Ensembl
ENSG00000079805
NCBI Gene
Aliases
CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P50570Dynamin-28701Ensembl, GeneID, HGNC

Source UniProt

Patents22

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026167077 A12026-08-137P50570Espacenet
JP 2026004568 A2026-01-1444421P50570Espacenet
EP 4650780 A22025-11-197197P50570Espacenet
EP 4641201 A22025-10-297125P50570Espacenet
JP 2025517969 A2025-06-127125P50570Espacenet
JP 2025517970 A2025-06-127197P50570Espacenet
JP 2023123507 A2023-09-0541P50570Espacenet
US 11446398 B22022-09-2025963P50570Espacenet
JP 2022524081 A2022-04-27128934P50570Espacenet
US 11078247 B22021-08-033189P50570Espacenet

1 to 10 of 22

See all 22 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,224

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDNM2 papersNewest fiscal year
P30DK084567Mayo Center for Cell Signaling in Gastroenterology192025
R01GM102187Chemical Tools for Probing Cysteine Sulfenation and Sulfination Redox Biology152025
R35GM118149Actin assembly and clathrin-mediated endocytosis in yeast and mammals112025
P30DK045735Yale Diabetes Research Center92025
P30DA018343Yale/NIDA Neuroproteomics Center82025
P30CA021765Cancer Center Support Grant (CCSG)72025
ZIANS003129Molecular and Clinical Manifestations of Matrix and Aggregate Myopathies72025
P30CA016672Cancer Center Support Grant62025
P40OD010440Caenorhabditis Genetics Center52025
R01AA020735Altered Lipid Droplet Trafficking: Role in Alcoholic Fatty Liver Disease52025

1 to 10 of 2,224Source NIH's project files

See all 2,224 nih grants

Papers3,066

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Dynamin-2 promotes Atg9A retrieval from phagophores during autophagy.Biol Open202642779336PubTator, text miningPubMed
Identification of immune cell mitochondrial dysfunction characteristics and clinical predictive biomarkers in sepsis via multi-cohort machine learning and single-cell RNA sequencing.Inflamm Res202642762293PubTator, text miningPubMed
Neuronal Apoptotic Bodies Facilitate Japanese Encephalitis Virus Infection and Pathogenicity.J Extracell Vesicles202642680695PubTator, text miningPubMed
Vasopressin boosts the antiproliferative effect of dynasore and wortmannin in triple-negative breast cancer cells.Med Oncol202642667529PubTator, text miningPubMed
The absorption and endocytosis mechanism of flaxseed cyclic peptide CLQ is mediated by its binding to clathrin.Food Res Int202642632707PubTator, text miningPubMed
Clinical, histopathological, and biomarker characterization of XLMTM and ADCNM: Operational lessons, screening and baseline data of the Unite-CNM study.J Neuromuscul Dis202642600180PubTator, text miningPubMed
Sulfonadyn Compounds: A Class of Aryl Sulfonamides That Inhibit Dynamin GTPase and Clathrin-Mediated Endocytosis and Are Antiepileptic in Animal Models.ACS Chem Biol202642313002PubTator, text miningPubMed
Metformin Activates AMP-Activated Protein Kinase-Transcription Factor EB Signaling to Restore Lysosomal and Mitochondrial Homeostasis and Suppress Epithelial-to-Mesenchymal Transition in Oxidative Stress-Injured Retinal Pigment Epithelium.
Am J Pathol202642276413PubTator, text miningPubMed
Beyond Membrane Remodeling: Organelle Crosstalk and Convergent Pathology in Centronuclear Myopathy.Muscles202642201138PubTator, text miningPubMed
Plasminogen Activator Inhibitor-1 is Internalized by Endothelial Cells via A Pinocytosis-Like Mechanism and Evades Degradation.FASEB J202642165362PubTator, text miningPubMed

1 to 10 of 3,066

See all 3,066 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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GET https://conductscience.org/api/genes/v1/1785/patents?page=2