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DNMT3B: DNA methyltransferase 3 beta

1 protein, 52 patents, 0 drugs, 0 trials, 5,127 NIH grants and 10,653 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolDNMT3BHGNC
NameDNA methyltransferase 3 betaHGNC
NCBI Gene ID1789NCBI Gene
HGNC IDHGNC:2979HGNC
EnsemblENSG00000088305NCBI Gene
AliasesFSHD4, ICF, ICF1, M.HsaIIIBNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9UBC3DNA (cytosine-5)-methyltransferase 3B85347Ensembl, GeneID, HGNCUniProt

Patents 52

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4805378 A12026-09-16579Q9UBC3Espacenet
JP 2026523341 A2026-07-141030Q9UBC3Espacenet
EP 4771137 A12026-07-08576Q9UBC3Espacenet
EP 4771157 A12026-07-08576Q9UBC3Espacenet
US 12649003 B22026-06-091030Q9UBC3Espacenet
JP 2026510339 A2026-04-02576Q9UBC3Espacenet
EP 4713451 A22026-03-25576Q9UBC3Espacenet
EP 4713452 A22026-03-25576Q9UBC3Espacenet
US 12558437 B22026-02-241030Q9UBC3Espacenet
EP 4677082 A22026-01-14576Q9UBC3Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5127

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant472,025NIH's project files
P30CA008748Cancer Center Support Grant342,025NIH's project files
P30CA006973Regional Oncology Research Center242,025NIH's project files
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)192,025NIH's project files
P30CA016058Cancer Center Support Grant192,025NIH's project files
R01CA178441Combinatorial epigenetic-based prevention of breast cancer182,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant172,025NIH's project files
R35GM119721Diversity Supplement: Mechanistic Insights into Mammalian DNA Methylation162,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant152,025NIH's project files
P30CA016086Cancer Center Support Grant132,025NIH's project files

Papers 10653

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42792998PubTator, text miningPubMed
42788794PubTator, text miningPubMed
42780834PubTator, text miningPubMed
42765620PubTator, text miningPubMed
42727849PubTator, text miningPubMed
42707300PubTator, text miningPubMed
42677956PubTator, text miningPubMed
42647205PubTator, text miningPubMed
42597495PubTator, text miningPubMed
42591630PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license