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Gene · 1808

DPYSL2: dihydropyrimidinase like 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DPYSL2: dihydropyrimidinase like 2. Genes, record 1808. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1808

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Gene

Symbol
DPYSL2
HGNC
Name
dihydropyrimidinase like 2
HGNC
NCBI Gene ID
1808
NCBI Gene
HGNC ID
HGNC:3014
HGNC
Ensembl
ENSG00000092964
NCBI Gene
Aliases
CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16555Dihydropyrimidinase-related protein 257215Ensembl, GeneID, HGNC

Source UniProt

Patents57

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1443787Q16555Espacenet
JP 2026004568 A2026-01-1443789Q16555Espacenet
EP 4650780 A22025-11-194628Q16555Espacenet
EP 4641202 A22025-10-294849Q16555Espacenet
JP 2025517970 A2025-06-124628Q16555Espacenet
KR 1020250017231 A2025-02-044849Q16555Espacenet
JP 2024009871 A2024-01-2397Q16555Espacenet
KR 1020240002810 A2024-01-086Q16555Espacenet
US 11446398 B22022-09-2024397Q16555Espacenet
JP 2022524081 A2022-04-27127368Q16555Espacenet

1 to 10 of 57

See all 57 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,023

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDPYSL2 papersNewest fiscal year
P30MH062512HIV Neurobehavioral Research Center52025
P50HD103526MIND Institute Intellectual and Developmental Disabilities Research Center52025
F32NS128392Neuropeptide Y1 Receptor-Expressing Neurons in the Lateral Parabrachial Nucleus in Neuropathic Pain42025
P30CA016672Cancer Center Support Grant42025
P30ES023513UC Davis Environmental Health Sciences Core Center42025
K00NS124190Dissecting the Parabrachial Nucleus's Role in the Development and Maintenance of Neuropathic Pain32025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant32025
P30ES005605Environmental Health Sciences Research Center32025
P30EY010572Ophthalmology Core Facility32025
P60AA011605Molecular and Circuit Pathogenesis of Alcohol Use Disorders32025

1 to 10 of 1,023Source NIH's project files

See all 1,023 nih grants

Papers1,564

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Peripheral NaV1.7 modulation reveals divergent peripheral and central adaptations in persistent trigeminal pain.bioRxiv202642818013PubTator, text miningPubMed
Microtubule Cytoskeleton Dysfunction in Chronic Pain: Mechanisms of Transport Failure and Emerging Therapeutic Targets.Int J Mol Sci202642794564PubTator, text miningPubMed
NaV1.7-dependent peripheral sensitization drives chronic pain in Parkinson's disease.bioRxiv202642780151PubTator, text miningPubMed
The Fbxw11-Dpysl2 ubiquitin axis restrains the progression of acute myeloid leukemia.Cancer Lett202642586305PubTator, text miningPubMed
Microtubules in Spinal Cord Injury: From Cytoskeletal Dysregulation to Therapeutic Regeneration.J Neurochem202642563243PubTator, text miningPubMed
Gene variants associated with pediatric-onset erythromelalgia: Mendelian and rare-variant association analyses.Pain Rep202642559536PubTator, text miningPubMed
Targeting CRMP2 for Chronic Pain: From Molecular Mechanisms to Therapeutic Strategies.Biomedicines202642511986PubTator, text miningPubMed
Analytical Validation of an ELISA Assay for Maternal Autoantibody-Related Autism.Diagnostics (Basel)202642279533PubTator, text miningPubMed
Mapping Phosphorylation-Specific Pin1-CRMP2 Interactions Using an Integrated Mass Spectrometry Approach.ACS Chem Biol202642186247PubTator, text miningPubMed
Acidosis Regulates Microtubule Dynamics via the β1 Integrin/RhoA/CRMP-2 Axis.J Am Chem Soc202642159342PubTator, text miningPubMed

1 to 10 of 1,564

See all 1,564 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1808

GET https://conductscience.org/api/genes/v1/1808/patents?page=2