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Gene · 1810

DR1: down-regulator of transcription 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DR1: down-regulator of transcription 1. Genes, record 1810. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1810

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Gene

Symbol
DR1
HGNC
Name
down-regulator of transcription 1
HGNC
NCBI Gene ID
1810
NCBI Gene
HGNC ID
HGNC:3017
HGNC
Ensembl
ENSG00000117505
NCBI Gene
Aliases
NC2, NC2-BETA, NC2B, NCB2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q01658Protein Dr11761Ensembl, GeneID, HGNC

Source UniProt

Patents42

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444263Q01658Espacenet
JP 2026004568 A2026-01-1444264Q01658Espacenet
EP 4650780 A22025-11-198752Q01658Espacenet
JP 2025147176 A2025-10-0614898Q01658Espacenet
JP 2025517970 A2025-06-128752Q01658Espacenet
JP 2025028160 A2025-02-2814898Q01658Espacenet
KR 1020250010750 A2025-01-2114898Q01658Espacenet
JP 2024109657 A2024-08-1414737Q01658Espacenet
KR 1020240010752 A2024-01-24174Q01658Espacenet
JP 2023165849 A2023-11-17174Q01658Espacenet

1 to 10 of 42

See all 42 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,773

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDR1 papersNewest fiscal year
P01CA022443Molecular Biology and Genetics of Human Tumor Viruses72025
P30CA008748Cancer Center Support Grant62025
P30CA006973Regional Oncology Research Center52025
P30CA016672Cancer Center Support Grant52025
P01CA018029Adult Leukemia Research Center32025
P30CA006927Comprehensive Cancer Center Program at Fox Chase32025
P30CA014520UW Comprehensive Cancer Center Support32025
P30CA023108Cancer Center Support Grant32025
R01AI110762Molecular Mechanisms of HBV cccDNA Formation32025
R01DK018381Studies on the structure of basement membranes32025

1 to 10 of 1,773Source NIH's project files

See all 1,773 nih grants

Papers3,137

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Reply to 'DR1-DR2 enrichment in HBeAg-negative chronic hepatitis B: integration hotspot or survivor signature?'Gut202642810849PubTator, text miningPubMed
Mesoporous cerium oxide decorated nickel-based metal-organic frameworks for diffusion-driven charge storage in symmetric aqueous supercapacitors.RSC Adv202642657173PubTator, text miningPubMed
Multi-protease supplementation enhances growth performance and promotes gut health in broilers fed low-protein, low-amino acid diets.Transl Anim Sci202642516357PubTator, text miningPubMed
Integrated D4Z4 structural, epigenetic and exome-based evaluation of facioscapulohumeral muscular dystrophy in a tertiary referral cohort from Türkiye.J Med Genet202642498520PubTator, text miningPubMed
DR1-DR2 enrichment in HBeAg-negative chronic hepatitis B: integration hotspot or survivor signature?Gut202642457619PubTator, text miningPubMed
AI-aided design of multi-epitope peptide vaccine elicits cellular and humoral immunity to broad Omicron subvariants.Zool Res202642339725PubTator, text miningPubMed
Nano-Fe3C/Fe In Situ Deposited on N-Doped Carbon Aerogel for Tunable Microwave Absorption within Ultralow Filler Loading.ACS Appl Mater Interfaces202642332923PubTator, text miningPubMed
Retraction: Aqua-soluble DDQ reduces the levels of Dr1 and Ab and inhibits abnormal interactions between Ab and Dr1 and protects Alzheimer's disease neurons from Ab- and Dr1-induced mitochondrial and synaptic toxicities.
Hum Mol Genet202642307453PubTator, text miningPubMed
High performance organic solar cell enabled by manipulating the exciton dissociation and charge transfer via dielectric engineering.Nat Commun202642303629PubTator, text miningPubMed
HLA-DR Haplotype Diversity Revealed by Pangenome Sequence Analysis.HLA202642249699PubTator, text miningPubMed

1 to 10 of 3,137

See all 3,137 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1810

GET https://conductscience.org/api/genes/v1/1810/patents?page=2