Gene · 1810
DR1: down-regulator of transcription 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DR1: down-regulator of transcription 1. Genes, record 1810. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1810
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q01658 | Protein Dr1 | 176 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents42
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 44263 | Q01658 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 44264 | Q01658 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8752 | Q01658 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 14898 | Q01658 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 8752 | Q01658 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 14898 | Q01658 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 14898 | Q01658 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14737 | Q01658 | Espacenet |
| KR 1020240010752 A | 2024-01-24 | 174 | Q01658 | Espacenet |
| JP 2023165849 A | 2023-11-17 | 174 | Q01658 | Espacenet |
1 to 10 of 42
See all 42 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,773
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DR1 papers | Newest fiscal year |
|---|---|---|---|
| P01CA022443 | Molecular Biology and Genetics of Human Tumor Viruses | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P01CA018029 | Adult Leukemia Research Center | 3 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 3 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 3 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 3 | 2025 |
| R01AI110762 | Molecular Mechanisms of HBV cccDNA Formation | 3 | 2025 |
| R01DK018381 | Studies on the structure of basement membranes | 3 | 2025 |
1 to 10 of 1,773Source NIH's project files
See all 1,773 nih grantsPapers3,137
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Reply to 'DR1-DR2 enrichment in HBeAg-negative chronic hepatitis B: integration hotspot or survivor signature?' | Gut | 2026 | 42810849 | PubTator, text mining | PubMed |
| Mesoporous cerium oxide decorated nickel-based metal-organic frameworks for diffusion-driven charge storage in symmetric aqueous supercapacitors. | RSC Adv | 2026 | 42657173 | PubTator, text mining | PubMed |
| Multi-protease supplementation enhances growth performance and promotes gut health in broilers fed low-protein, low-amino acid diets. | Transl Anim Sci | 2026 | 42516357 | PubTator, text mining | PubMed |
| Integrated D4Z4 structural, epigenetic and exome-based evaluation of facioscapulohumeral muscular dystrophy in a tertiary referral cohort from Türkiye. | J Med Genet | 2026 | 42498520 | PubTator, text mining | PubMed |
| DR1-DR2 enrichment in HBeAg-negative chronic hepatitis B: integration hotspot or survivor signature? | Gut | 2026 | 42457619 | PubTator, text mining | PubMed |
| AI-aided design of multi-epitope peptide vaccine elicits cellular and humoral immunity to broad Omicron subvariants. | Zool Res | 2026 | 42339725 | PubTator, text mining | PubMed |
| Nano-Fe3C/Fe In Situ Deposited on N-Doped Carbon Aerogel for Tunable Microwave Absorption within Ultralow Filler Loading. | ACS Appl Mater Interfaces | 2026 | 42332923 | PubTator, text mining | PubMed |
Retraction: Aqua-soluble DDQ reduces the levels of Dr1 and Ab and inhibits abnormal interactions between Ab and Dr1 and protects Alzheimer's disease neurons from Ab- and Dr1-induced mitochondrial and synaptic toxicities. | Hum Mol Genet | 2026 | 42307453 | PubTator, text mining | PubMed |
| High performance organic solar cell enabled by manipulating the exciton dissociation and charge transfer via dielectric engineering. | Nat Commun | 2026 | 42303629 | PubTator, text mining | PubMed |
| HLA-DR Haplotype Diversity Revealed by Pangenome Sequence Analysis. | HLA | 2026 | 42249699 | PubTator, text mining | PubMed |
1 to 10 of 3,137
See all 3,137 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1810
GET https://conductscience.org/api/genes/v1/1810/patents?page=2