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Gene · 1815

DRD4: dopamine receptor D4

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. DRD4: dopamine receptor D4. Genes, record 1815. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/1815

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
DRD4
HGNC
Name
dopamine receptor D4
HGNC
NCBI Gene ID
1815
NCBI Gene
HGNC ID
HGNC:3025
HGNC
Ensembl
ENSG00000069696
NCBI Gene
Aliases
D4DR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P21917Dopamine receptor D44193Ensembl, GeneID, HGNC

Source UniProt

Patents16

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444206P21917Espacenet
JP 2025529142 A2025-09-041321P21917Espacenet
US 12371689 B22025-07-291321P21917Espacenet
US 11446398 B22022-09-2025464P21917Espacenet
US 11446398 B22022-09-2025465P21917Espacenet
US 11400116 B22022-08-02256P21917Espacenet
JP 2022524081 A2022-04-27128435P21917Espacenet
JP 2022524081 A2022-04-27128436P21917Espacenet
US 11078247 B22021-08-033263P21917Espacenet
US 10772934 B22020-09-151174P21917Espacenet

1 to 10 of 16

See all 16 patents

Drugs36

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AMOXAPINECHEMBL1113Dopamine receptor antagonistANTAGONISTChEMBL
APOMORPHINECHEMBL53D2-like dopamine receptor agonistAGONISTChEMBL
APOMORPHINE HYDROCHLORIDECHEMBL3187985D2-like dopamine receptor agonistAGONISTChEMBL
BROMOCRIPTINECHEMBL493D2-like dopamine receptor agonistAGONISTChEMBL
BROMOCRIPTINE MESYLATECHEMBL1200503D2-like dopamine receptor agonistAGONISTChEMBL
CHLORPROMAZINECHEMBL71D2-like dopamine receptor antagonistANTAGONISTChEMBL
CHLORPROMAZINE HYDROCHLORIDECHEMBL1713D2-like dopamine receptor antagonistANTAGONISTChEMBL
CLOTHIAPINECHEMBL304902Dopamine D4 receptor antagonistANTAGONISTChEMBL
DROPERIDOLCHEMBL1108D2-like dopamine receptor antagonistANTAGONISTChEMBL
ERGOLOIDCHEMBL2364968Dopamine receptor agonistAGONISTChEMBL

1 to 10 of 36

See all 36 drugs

Trials657

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants2,711

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).152025
ZIAAA000550Neurobiology of Drug Reward and Addiction142025
ZIADA000493Functional and Pharmacological Significance of Receptor Heteromers in the CNS142025
ZIAAA000301Integrative genetics of behavior with high throughput technologies122025
P50HD027802Differential Diagnosis in Learning Disabilities102025
ZIANS002263Molecular And Pharmacological Studies Of Dopamine Receptors92025
T32AA007459Alcohol Intervention Treatment Outcome Research Training82025
ZIAHG000175Genetic Analysis of Attention Deficit Hyperactivity Disorder82025
R01HD036916Fragile Families and Child Wellbeing - Young Adulthood72025
R35GM122481Development and Testing of New Computational Methods for Ligand Discovery and Mechanism62025

1 to 10 of 2,711Source NIH's project files

See all 2,711 nih grants

Papers4,548

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42690169PubTator, text miningPubMed
42555991PubTator, text miningPubMed
42540671PubTator, text miningPubMed
42540002PubTator, text miningPubMed
42477902PubTator, text miningPubMed
42345644PubTator, text miningPubMed
42292415PubTator, text miningPubMed
42241225PubTator, text miningPubMed
42172180PubTator, text miningPubMed
42064146PubTator, text miningPubMed

1 to 10 of 4,548

See all 4,548 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1815

GET https://conductscience.org/api/genes/v1/1815/patents