ConductScience.org, home

Gene · 1827

RCAN1: regulator of calcineurin 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. RCAN1: regulator of calcineurin 1. Genes, record 1827. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1827

On this page

Gene

Symbol
RCAN1
HGNC
Name
regulator of calcineurin 1
HGNC
NCBI Gene ID
1827
NCBI Gene
HGNC ID
HGNC:3040
HGNC
Ensembl
ENSG00000159200
NCBI Gene
Aliases
ADAPT78, CSP1, DSCR1, MCIP1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P53805Calcipressin-12521Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461238P53805Espacenet
EP 4650780 A22025-11-195333P53805Espacenet
JP 2025517970 A2025-06-125333P53805Espacenet
US 11446398 B22022-09-2072269P53805Espacenet
JP 2022524081 A2022-04-27175240P53805Espacenet
JP 2019054813 A2019-04-11241673P53805Espacenet
EP 3403091 A12018-11-21715P53805Espacenet
JP 2017121241 A2017-07-13241673P53805Espacenet
US 9695419 B22017-07-0471P53805Espacenet
JP 2016204379 A2016-12-0875P53805Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,028

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRCAN1 papersNewest fiscal year
R01NS080946Role of DYRK1A/MNB in synaptic growth and function42025
P30CA046934University of Colorado Cancer Center Support Grant32025
R35GM136243Elucidating calcineurin signaling mechanisms at membranes32025
U19AG068054Alzheimer Biomarker Consortium - Down Syndrome (ABC-DS)32025
P30AG038070Nathan Shock Center for Excellence in Basic Biology of Aging22025
P30AG066519The Alzheimer's Disease Research Center at the University of California, Irvine22025
P30CA014051Cancer Center Support (Core) Grant22025
P30CA016056Roswell Park Cancer Center Support Grant22025
P30CA016058Cancer Center Support Grant22025
P30CA016086Cancer Center Support Grant22025

1 to 10 of 1,028Source NIH's project files

See all 1,028 nih grants

Papers1,437

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Circ_0001490/miR-330-3p/RCAN1 Signaling Defines a ceRNA Network Associated with Rheumatic Heart Disease Progression.Ann Clin Lab Sci202642790940PubTator, text miningPubMed
Oxidative stress induces porcine RCAN1-1L to promote mitophagy and enhance PRRSV replication.Dev Comp Immunol202642763026PubTator, text miningPubMed
Advanced esophageal adenocarcinoma in a pediatric patient with Down syndrome: a rare case report and literature review.Ann Med Surg (Lond)202642725202PubTator, text miningPubMed
Integrated Bulk and Single-Cell Transcriptomic Analysis Identifies a Reproducible SASP-Related Three-Gene Panel and Prioritizes CFB as a Fibroblast-Associated Marker in Rheumatoid Arthritis.Genes (Basel)202642510776PubTator, text miningPubMed
First- and Second-Trimester Cardiovascular Anomalies in Trisomy 21 Fetuses: Anatomy, Embryology, Genetics and Imaging.J Pers Med202642506084PubTator, text miningPubMed
The Role of Genetic Alterations in the Emergence of Alzheimer's Disease in Down Syndrome: A Review.Eur J Neurosci202642442802PubTator, text miningPubMed
SUMO3/RUNX1/AIRE/RCAN1 and DNMT3L/DYRK1A/Let-7c-5p/VEGF axes: immune dysregulation and genetic susceptibility as pulmonary risk factors in Down syndrome.3 Biotech202642245386PubTator, text miningPubMed
RNA-binding protein RCAN1.1L modulates ATF2 mRNA stability to promote mitochondrial fission in acute ischemic stroke.Cell Death Dis202642129133PubTator, text miningPubMed
Mechanically Induced Adaptive Self-Growing Protein Hydrogel.Adv Mater202642068201PubTator, text miningPubMed
Peripheral blood biomarkers RCAN1, Clusterin, RAGE, and malondialdehyde for early diagnosis and progression of Alzheimer's disease.BMC Med202642045900PubTator, text miningPubMed

1 to 10 of 1,437

See all 1,437 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1827

GET https://conductscience.org/api/genes/v1/1827/patents?page=2