Gene · 1829
DSG2: desmoglein 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DSG2: desmoglein 2. Genes, record 1829. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1829
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q14126 | Desmoglein-2 | 1,118 | 12 | Ensembl, GeneID, HGNC |
Source UniProt
Patents73
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4824266 A1 | 2026-10-21 | 70 | Q14126 | Espacenet |
| EP 4791437 A1 | 2026-08-19 | 68 | Q14126 | Espacenet |
| EP 4773979 A1 | 2026-07-15 | 190 | Q14126 | Espacenet |
| EP 4705273 A2 | 2026-03-11 | 505 | Q14126 | Espacenet |
| US 12564647 B2 | 2026-03-03 | 224 | Q14126 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 43667 | Q14126 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1918 | Q14126 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1507 | Q14126 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 4446 | Q14126 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1331 | Q14126 | Espacenet |
1 to 10 of 73
See all 73 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,602
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DSG2 papers | Newest fiscal year |
|---|---|---|---|
| R01AR041836 | Function of Desmoglein 1/Pemphigus Foliaceus Antigen | 34 | 2025 |
| R01AR043380 | Desmoplakin Assembly and Function in Epidermis | 17 | 2025 |
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 17 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 9 | 2025 |
| R01DK079392 | Intestinal Inflammation: Signaling proteins and the rate of PMN transmigration | 9 | 2025 |
| T32CA009560 | Carcinogenesis Training Program | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| T32AR007465 | Penn Dermatology Research Training Program | 6 | 2025 |
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,602Source NIH's project files
See all 1,602 nih grantsPapers2,548
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Desmoglein-2 F833C Is Predicted to Disrupt Hydrophobic Interactions With the Armadillo Repeat Region 1 of Plakoglobin. | Cureus | 2026 | 42781589 | PubTator, text mining | PubMed |
| Generation of an induced pluripotent stem cell line, JHUi010-A, from an arrhythmogenic cardiomyopathy patient harboring pathogenic DSG2 variant c.2358delA. | Stem Cell Res | 2026 | 42762668 | PubTator, text mining | PubMed |
| Heterologous cell-cell junctions support transepithelial endometrial trophoblast invasion in human. | Mol Hum Reprod | 2026 | 42714239 | PubTator, text mining | PubMed |
| FASN-mediated de novo lipogenesis promotes ceramide accumulation and myocardial damage in arrhythmogenic cardiomyopathy. | iScience | 2026 | 42701407 | PubTator, text mining | PubMed |
| DSG2 Expression Marks a Stromal-Immune Organizational State in Head and Neck Squamous Cell Carcinoma. | Cancers (Basel) | 2026 | 42649925 | PubTator, text mining | PubMed |
| Inflammatory Hot Phases in Arrhythmogenic Cardiomyopathy: A Dynamic Electrophysiologic Substrate Beyond Scar. | JACC Adv | 2026 | 42628220 | PubTator, text mining | PubMed |
| Breaking bad and taking sides: chamber-specific mitochondrial remodeling in Dsg2-linked arrhythmogenic cardiomyopathy. | Am J Physiol Heart Circ Physiol | 2026 | 42581678 | PubTator, text mining | PubMed |
| N-cadherin orientational order decreases with mechanical load at cardiomyocyte adherens junctions. | bioRxiv | 2026 | 42538992 | PubTator, text mining | PubMed |
| A Rho GTPase-related gene signature predicts prognosis and reveals an immunosuppressive microenvironment in lung adenocarcinoma: an integrated analysis of bulk and single-cell RNA sequencing data. | Sci Rep | 2026 | 42469385 | PubTator, text mining | PubMed |
| Exploring the CD38-Associated Surfaceome via Nanobody-Targeted TurboID. | Mol Cell Proteomics | 2026 | 42448231 | PubTator, text mining | PubMed |
1 to 10 of 2,548
See all 2,548 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1829
GET https://conductscience.org/api/genes/v1/1829/patents?page=2