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Gene · 1830

DSG3: desmoglein 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DSG3: desmoglein 3. Genes, record 1830. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1830

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Gene

Symbol
DSG3
HGNC
Name
desmoglein 3
HGNC
NCBI Gene ID
1830
NCBI Gene
HGNC ID
HGNC:3050
HGNC
Ensembl
ENSG00000134757
NCBI Gene
Aliases
ABOLM, CDHF6, PVA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P32926Desmoglein-39991Ensembl, GeneID, HGNC

Source UniProt

Patents34

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4670794 A22025-12-319P32926Espacenet
JP 2025541179 A2025-12-1830P32926Espacenet
EP 4650780 A22025-11-191617P32926Espacenet
EP 4641201 A22025-10-291224P32926Espacenet
EP 4630459 A12025-10-1530P32926Espacenet
JP 2025529142 A2025-09-041332P32926Espacenet
US 12371689 B22025-07-291332P32926Espacenet
JP 2025517969 A2025-06-121224P32926Espacenet
JP 2025517970 A2025-06-121617P32926Espacenet
JP 2024546842 A2024-12-265P32926Espacenet

1 to 10 of 34

See all 34 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants846

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDSG3 papersNewest fiscal year
R01AR041836Function of Desmoglein 1/Pemphigus Foliaceus Antigen252025
T32AR007465Penn Dermatology Research Training Program172025
R01AR043380Desmoplakin Assembly and Function in Epidermis122025
P30AR069589Penn Skin Biology and Diseases Resource-based Center112025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center112025
R01CA228196Role of Desmoglein 1 in Keratinocyte-Melanocyte Communication and Melanoma62025
P20GM113126Nebraska Center for Integrated Biomolecular Communication (CIBC)52025
P30CA008748Cancer Center Support Grant52025
R01AI114780Mechanisms of autoimmunity in myasthenia gravis52025
R35GM119617Cell junction and nuclear forces as mediators of epithelial cell homeostasis52025

1 to 10 of 846Source NIH's project files

See all 846 nih grants

Papers2,614

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Clinical improvement of pemphigus-like mucocutaneous disease in a patient with CLL following initiation of zanubrutinib: a case report.Front Immunol202642812523PubTator, text miningPubMed
Two opposite effects of desmoglein 3 on the growth of oral squamous cell carcinoma between anchorage -dependent and -independent conditions.PLoS One202642789540PubTator, text miningPubMed
Coexistence of Erythrodermic Psoriasis and Bullous Pemphigoid: A Case Report.Clin Cosmet Investig Dermatol202642770037PubTator, text miningPubMed
Efficacy and safety of subcutaneous efgartigimod with prednisone in moderate-to-severe pemphigus (ADDRESS): a global, phase III, randomised controlled, double-blind trial.Br J Dermatol202642723554PubTator, text miningPubMed
Case report: Atypical SJS/TEN-like fulminant pemphigus vulgaris: diagnostic challenges and the potential impact of anti-Dsg1 titers and CMV reactivation.Front Immunol202642698938PubTator, text miningPubMed
Acantholytic Blistering of the Oroesophageal Mucosa Due to Homozygous DSG3 Pathogenic Missense Variant.JAMA Dermatol202642684697PubTator, text miningPubMed
Rituximab remodels the circulating immune landscape in pemphigus vulgaris revealed by high-dimensional immune profiling.J Transl Autoimmun202642602981PubTator, text miningPubMed
IgG subclasses and their significance in pemphigus disease progression monitoring.Front Immunol202642591548PubTator, text miningPubMed
Anti-BP180 Mucosal Membrane Pemphigoid With a History of Maxillary Carcinoma With Antibodies to 190 kDa Periplakin and 210 kDa Envoplakin: A Case Report.J Dermatol202642543823PubTator, text miningPubMed
Chemiluminescence Immunoassay and Enzyme-Linked Immunosorbent Assay in the Diagnosis of Pemphigoid and Pemphigus: A Comparative Study.Int J Mol Sci202642511614PubTator, text miningPubMed

1 to 10 of 2,614

See all 2,614 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1830

GET https://conductscience.org/api/genes/v1/1830/patents?page=2