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Gene · 1831

TSC22D3: TSC22 domain family member 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TSC22D3: TSC22 domain family member 3. Genes, record 1831. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1831

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Gene

Symbol
TSC22D3
HGNC
Name
TSC22 domain family member 3
HGNC
NCBI Gene ID
1831
NCBI Gene
HGNC ID
HGNC:3051
HGNC
Ensembl
ENSG00000157514
NCBI Gene
Aliases
DIP, DSIPI, GILZ, TSC-22R, hDIP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99576TSC22 domain family protein 31340Ensembl, GeneID, HGNC

Source UniProt

Patents57

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468459Q99576Espacenet
EP 4650780 A22025-11-199097Q99576Espacenet
EP 4641201 A22025-10-299368Q99576Espacenet
EP 4641202 A22025-10-295548Q99576Espacenet
JP 2025147176 A2025-10-0615806Q99576Espacenet
JP 2025517969 A2025-06-129368Q99576Espacenet
JP 2025517970 A2025-06-129097Q99576Espacenet
JP 2025032204 A2025-03-1137756Q99576Espacenet
JP 2025028160 A2025-02-2815806Q99576Espacenet
KR 1020250017231 A2025-02-045548Q99576Espacenet

1 to 10 of 57

See all 57 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants964

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTSC22D3 papersNewest fiscal year
ZIAES090057Glucocorticoid Hormone Action112025
ZICES102445Gene Expression and Microarrays72025
P30CA014599Cancer Center Support Grant52025
P30ES013508Center of Excellence in Environmental Toxicology52025
R01DK056695SGK Regulation of Epithelial Sodium Transport52025
P30CA008748Cancer Center Support Grant42025
P30CA016672Cancer Center Support Grant42025
R01HL109557Mechanisms and Consequences of Gene Induction by Glucocorticoids in Airway Smooth Muscle42025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center32025
P30ES006694Southwest Environmental Health Sciences Center32025

1 to 10 of 964Source NIH's project files

See all 964 nih grants

Papers1,374

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Immune dysregulation and stem-like CD8+ T cell enrichment in type 1 diabetes pancreatic lymph nodes.J Clin Invest202642741944PubTator, text miningPubMed
SIRT2 deacylase modulators control B cell metabolic reprogramming in EBV infection and mitogenic activation.Proc Natl Acad Sci U S A202642636358PubTator, text miningPubMed
TSC22D3-Mediated Quiescence Preservation Boosts HSC Engraftment in Xenografts.Biomedicines202642511899PubTator, text miningPubMed
Glucocorticoid Signaling in PSC-Derived Neural Systems to Elucidate Mechanisms of Stress-Induced Psychiatric Vulnerability.Mol Neurobiol202642412256PubTator, text miningPubMed
Glucocorticoid-induced Leucine Zipper (GILZ) is a novel secreted protein by intestinal L-cells and is dysregulated during active ulcerative colitis.Cell Death Discov202642310308PubTator, text miningPubMed
Characterization of Isoorientin and Paeoniflorin as Botanical Glucocorticoid Receptor Modulators from White Peony and Chasteberry.Nutrients202642196951PubTator, text miningPubMed
The autophagy-inhibitory tissue hormone DBI/ACBP is essential for glucocorticoid-induced immunosuppression.Autophagy202642070152PubTator, text miningPubMed
The cardiovascular-immune axis: crosstalk and therapy in atherosclerosis, myocarditis and vasculitis.Front Immunol202642023245PubTator, text miningPubMed
An AI-Enabled Single-Cell Transcriptomic Analysis Pipeline for Gene Signature Discovery in Natural Killer Cells Linked to Remission Outcomes in Chronic Myeloid Leukemia.Biology (Basel)202641972591PubTator, text miningPubMed
Aberrant immune regulation and enrichment of stem-like CD8+ T cells in the pancreatic lymph node during type 1 diabetes development.bioRxiv202641959012PubTator, text miningPubMed

1 to 10 of 1,374

See all 1,374 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1831

GET https://conductscience.org/api/genes/v1/1831/patents?page=2