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Gene · 1844

DUSP2: dual specificity phosphatase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DUSP2: dual specificity phosphatase 2. Genes, record 1844. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1844

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Gene

Symbol
DUSP2
HGNC
Name
dual specificity phosphatase 2
HGNC
NCBI Gene ID
1844
NCBI Gene
HGNC ID
HGNC:3068
HGNC
Ensembl
ENSG00000158050
NCBI Gene
Aliases
PAC-1, PAC1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q05923Dual specificity protein phosphatase 23141Ensembl, GeneID, HGNC

Source UniProt

Patents41

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4831300 A12026-10-28120Q05923Espacenet
JP 2026004568 A2026-01-1444337Q05923Espacenet
EP 4641201 A22025-10-292953Q05923Espacenet
EP 4641202 A22025-10-294696Q05923Espacenet
WO 2025217275 A22025-10-169Q05923Espacenet
JP 2025517969 A2025-06-122953Q05923Espacenet
KR 1020250017231 A2025-02-044696Q05923Espacenet
US 11446398 B22022-09-2025782Q05923Espacenet
JP 2022524081 A2022-04-27128753Q05923Espacenet
US 11078247 B22021-08-033318Q05923Espacenet

1 to 10 of 41

See all 41 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,190

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDUSP2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant92025
R01HL101972Characterization of Coagulation Factor-platelet Interactions: Role of FXI82025
P30CA016087Cancer Center Support Grant42025
R01HL019278Platelet Integrin AlphaIIbBeta3 Structure, Activation, and Ligand Binding: Fibrinogen, Fibrin, D-dimer, and von Willebrand Factor42025
P30CA015704Cancer Center Support Grant32025
P30CA036727Buffett Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025
R35GM141825Mechanisms of microtubule-based transport32025
UL1TR001445Clinical and Translational Science Award32025
UL1TR001863Yale Clinical and Translational Science Award32025

1 to 10 of 1,190Source NIH's project files

See all 1,190 nih grants

Papers2,214

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Impact of C-terminal amidation on platelet activation by protease-activated receptors 1 and 4 activating peptides: communication from the ISTH SSC Subcommittee on Platelets in Health and Disease.J Thromb Haemost202642810688PubTator, text miningPubMed
A functionally distinct HPA-1a-specific alloantibody associated with fetal/neonatal alloimmune thrombocytopenia that activates platelets via FcγRIIa.Transfusion202642799830PubTator, text miningPubMed
Picropodophyllotoxin Suppresses Factor Xa Activity, Platelet Aggregation, and Arterial Thrombosis.Biomolecules202642793169PubTator, text miningPubMed
Tofacitinib does not affect platelet function or coagulation in patients with ulcerative colitis.Front Immunol202642787274PubTator, text miningPubMed
Immune dysregulation and stem-like CD8+ T cell enrichment in type 1 diabetes pancreatic lymph nodes.J Clin Invest202642741944PubTator, text miningPubMed
Do Activated Platelets Contribute to Mild Bleeding in Severe Hemophilia A?Indian J Hematol Blood Transfus202642712744PubTator, text miningPubMed
Predicting Device-Induced Platelet Damage in Assisted Circulation Using a New Biophysical Model and Experimental Validation.Artif Organs202642698235PubTator, text miningPubMed
Case Report: longitudinal immunoglobulin abnormalities preceding IgA-λ MGUS and colonic DLBCL: a case suggesting immune-driven B-cell dysregulation.Front Oncol202642656467PubTator, text miningPubMed
Divergent Effects of GnRH Agonist and GnRH Antagonist Treatment on Platelet Activity and Transcriptome.JACC CardioOncol202642615451PubTator, text miningPubMed
Selective preservation of shear-dependent platelet adhesion during microvolume storage in a compact agitation system.Res Pract Thromb Haemost202642602486PubTator, text miningPubMed

1 to 10 of 2,214

See all 2,214 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1844

GET https://conductscience.org/api/genes/v1/1844/patents?page=2