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Gene · 1847

DUSP5: dual specificity phosphatase 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DUSP5: dual specificity phosphatase 5. Genes, record 1847. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1847

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Gene

Symbol
DUSP5
HGNC
Name
dual specificity phosphatase 5
HGNC
NCBI Gene ID
1847
NCBI Gene
HGNC ID
HGNC:3071
HGNC
Ensembl
ENSG00000138166
NCBI Gene
Aliases
DUSP, HVH3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16690Dual specificity protein phosphatase 53841Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4831300 A12026-10-2888Q16690Espacenet
JP 2026004568 A2026-01-1444342Q16690Espacenet
EP 4650780 A22025-11-198646Q16690Espacenet
EP 4641201 A22025-10-298817Q16690Espacenet
EP 4641202 A22025-10-295462Q16690Espacenet
JP 2025517969 A2025-06-128817Q16690Espacenet
JP 2025517970 A2025-06-128646Q16690Espacenet
JP 2025032204 A2025-03-1127552Q16690Espacenet
KR 1020250017231 A2025-02-045462Q16690Espacenet
EP 4461818 A22024-11-1327552Q16690Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,226

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDUSP5 papersNewest fiscal year
P30CA008748Cancer Center Support Grant122025
P30CA016672Cancer Center Support Grant102025
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged72025
P30CA046934University of Colorado Cancer Center Support Grant52025
P30CA033572Cancer Center Support Grant42025
P30CA045508CSHL Cancer Center Support Grant42025
P30CA068485Cancer Center Support Grant42025
R01HL117913The NOTCH Signaling Pathway in Large Vessel Vasculitis42025
P01CA163222Targetable epigenetic and transcriptional mechanisms in melanoma thatshape the microenvironment32025
P30CA076292Moffitt Cancer Center Support Grant32025

1 to 10 of 1,226Source NIH's project files

See all 1,226 nih grants

Papers1,652

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Molecular predictors of recurrence in vestibular schwannomas: a transcriptomic and RT-qPCR analysis.Eur Arch Otorhinolaryngol202642642532PubTator, text miningPubMed
Development of receptor and oncogene-responsive luciferase reporter vectors that are activated via kinase signaling to AP-1.Exp Hematol202642595074PubTator, text miningPubMed
DUSP5 contributes to platinum resistance in ovarian cancer: single-cell discovery and functional validation.Front Pharmacol202642564493PubTator, text miningPubMed
Executive Function and Epigenetic Markers in Youth Exposed to Family and Community Violence in Childhood.Dev Psychobiol202642543904PubTator, text miningPubMed
CRISPR screens identify targets to rescue age-related T cell dysfunction in cancer.Cell202642526438PubTator, text miningPubMed
The dual specificity phosphatase 2 act as distal regulatory node in T cell signaling.iScience202642519028PubTator, text miningPubMed
p53 and p21 Status Influences Cellular Response to Metformin in KRAS-Mutant HCT116 Colorectal Cancer Cells.Curr Issues Mol Biol202642510971PubTator, text miningPubMed
DUSP5 regulates ferroptosis in pancreatic cancer by down-regulating SCD1 expression via ERK1/2.Acta Biochim Biophys Sin (Shanghai)202642473698PubTator, text miningPubMed
Structural and biochemical analyses of a novel bacterial dual specificity phosphatase from Candidatus Chlorohelix allophototropha.J Microbiol202642457432PubTator, text miningPubMed
Crosstalk Between Immunometabolic Pathways in Non-Small Cell Lung Cancer.Immunol Invest202642427023PubTator, text miningPubMed

1 to 10 of 1,652

See all 1,652 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1847

GET https://conductscience.org/api/genes/v1/1847/patents?page=2