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AGTR1: angiotensin II receptor type 1

1 protein, 196 patents, 24 drugs, 1,034 trials, 4,396 NIH grants and 12,486 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolAGTR1HGNC
Nameangiotensin II receptor type 1HGNC
NCBI Gene ID185NCBI Gene
HGNC IDHGNC:336HGNC
EnsemblENSG00000144891NCBI Gene
AliasesAG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, ATR1, HAT1RNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P30556Type-1 angiotensin II receptor35911Ensembl, GeneID, HGNCUniProt

Patents 196

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026062654 A2026-04-1016P30556Espacenet
EP 4698223 A22026-02-2532P30556Espacenet
JP 2026004568 A2026-01-1437391P30556Espacenet
JP 2026004568 A2026-01-1437392P30556Espacenet
JP 2026004568 A2026-01-1437393P30556Espacenet
JP 2026004568 A2026-01-1437394P30556Espacenet
JP 2026004568 A2026-01-1437395P30556Espacenet
JP 2026004568 A2026-01-1437396P30556Espacenet
JP 2026004568 A2026-01-1437397P30556Espacenet
JP 2026004568 A2026-01-1437398P30556Espacenet

Drugs 24

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ANGIOTENSIN IICHEMBL408403Type-1 angiotensin II receptor agonistAGONISTChEMBL
ANGIOTENSIN II ACETATECHEMBL3989932Type-1 angiotensin II receptor agonistAGONISTChEMBL
AZILSARTANCHEMBL57242Type-1 angiotensin II receptor antagonistANTAGONISTChEMBL
AZILSARTAN KAMEDOXOMILCHEMBL2103795Type-1 angiotensin II receptor antagonistANTAGONISTChEMBL
AZILSARTAN MEDOXOMILCHEMBL2028661Type-1 angiotensin II receptor antagonistANTAGONISTChEMBL
CANDESARTANCHEMBL1016Type-1 angiotensin II receptor antagonistANTAGONISTChEMBL
CANDESARTAN CILEXETILCHEMBL1014Type-1 angiotensin II receptor antagonistANTAGONISTChEMBL
EPROSARTANCHEMBL813Type-1 angiotensin II receptor antagonistANTAGONISTChEMBL
EPROSARTAN MESYLATECHEMBL1200987Type-1 angiotensin II receptor antagonistANTAGONISTChEMBL
FIMASARTANCHEMBL1951143Type-1 angiotensin II receptor antagonistANTAGONISTChEMBL

Trials 1034

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07588932TELMISARTANEARLY_PHASE1ClinicalTrials.gov
NCT07586371LOSARTANPHASE2/PHASE3ClinicalTrials.gov
NCT07568275ANGIOTENSIN IIEARLY_PHASE1ClinicalTrials.gov
NCT07555301SPARSENTANClinicalTrials.gov
NCT07555054IRBESARTANPHASE2ClinicalTrials.gov
NCT07544888VALSARTANPHASE1ClinicalTrials.gov
NCT07513350LOSARTANClinicalTrials.gov
NCT07491718VALSARTANClinicalTrials.gov
NCT07458880VALSARTANClinicalTrials.gov
NCT07449000LOSARTANClinicalTrials.gov

NIH grants 4396

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01HL016037Molecular Regulation of Cardiovascular 7 TM Receptors352,025NIH's project files
P20GM121334Mississippi Center of Excellence in Perinatal Research, Phase 2262,025NIH's project files
T32HL105324Hypertension and Cardiorenal Research Training Program262,025NIH's project files
R01HL056687Mechanisms of Maladaptation in Heart Failure142,025NIH's project files
R01DK043140Mechanisms Leading to Adrenal Zonation112,025NIH's project files
R01HL134850Angiotensin receptor G protein signal switching in AgRP neurons in cardiometabolic control112,025NIH's project files
U54GM104940Louisiana Clinical and Translational Science Center112,025NIH's project files
P30AG021334Older Americans Independence Center102,025NIH's project files
UL1TR001881UCLA Clinical and Translational Science Institute102,025NIH's project files
P30CA016672Cancer Center Support Grant92,025NIH's project files

Papers 12486

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822228PubTator, text miningPubMed
42812766PubTator, text miningPubMed
42810331PubTator, text miningPubMed
42802134PubTator, text miningPubMed
42792698PubTator, text miningPubMed
42783788PubTator, text miningPubMed
42783407PubTator, text miningPubMed
42773333PubTator, text miningPubMed
42769579PubTator, text miningPubMed
42769334PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license