Gene · 1861
TOR1A: torsin family 1 member A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TOR1A: torsin family 1 member A. Genes, record 1861. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1861
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O14656 | Torsin-1A | 332 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents42
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 67248 | O14656 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7000 | O14656 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6875 | O14656 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 13653 | O14656 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7952 | O14656 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7952 | O14656 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6875 | O14656 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7000 | O14656 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 13653 | O14656 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 13653 | O14656 | Espacenet |
1 to 10 of 42
See all 42 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,368
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TOR1A papers | Newest fiscal year |
|---|---|---|---|
| R01DK032083 | Multiple Autoantigens, Multiple Epitopes of Type 1 Diabetes | 27 | 2025 |
| R01DK063158 | Role of Transglutaminase 2 in Celiac Sprue | 18 | 2025 |
| R01DC011805 | Imaging genetics of laryngeal dystonia | 15 | 2025 |
| P30DK017047 | Diabetes Research Center | 12 | 2025 |
| R01DK108868 | Insulin specific T cell response shaped by diabetes protective MHC class II molecules | 10 | 2025 |
| R01DK099317 | Islet-specific CD8 T cells in the pathogenesis of type 1 diabetes | 7 | 2025 |
| P01AI042288 | Immune Function and the Progression to Type 1 Diabetes | 6 | 2025 |
| R01NS058949 | Clinical, Genetic, and Cellular Consequences of Mutations In NA,K-ATPase ATP1A3 | 6 | 2025 |
| R01GM105672 | The mechanism of ESCRT-mediated surveillance of the nuclear envelope barrier | 5 | 2025 |
| T32DK063687 | Developing Pediatric Endocrinologist for the Future | 5 | 2025 |
1 to 10 of 1,368Source NIH's project files
See all 1,368 nih grantsPapers3,348
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Founder mutations in movement disorders: global distribution, molecular mechanisms, and clinical consequences-a scoping review. | Neurogenetics | 2026 | 42825921 | PubTator, text mining | PubMed |
| A Protective Haplotype in trans Modifies Penetrance and Severity of TOR1A Dystonia. | medRxiv | 2026 | 42818409 | PubTator, text mining | PubMed |
| [Genetic Dystonias]. | Medicina (B Aires) | 2026 | 42659549 | PubTator, text mining | PubMed |
| Child Neurology: Early-Onset, Rapidly Progressive, and Refractory DYT-TOR1A Status Dystonicus. | Neurology | 2026 | 42551000 | PubTator, text mining | PubMed |
| Integrative chemical genetics platform identifies condensate modulators linked to neurological disorders. | Mol Biol Cell | 2026 | 42418712 | PubTator, text mining | PubMed |
| The Biological Fate of DBS Leads After 15 Years of Stimulation. | Mov Disord Clin Pract | 2026 | 42321150 | PubTator, text mining | PubMed |
| The genetic landscape of childhood-onset dystonia in a nationwide Turkish cohort: Clinical spectrum, molecular diagnostics, and therapeutic implications. | Eur J Paediatr Neurol | 2026 | 42308683 | PubTator, text mining | PubMed |
| Assessing vocal changes through spectral analyses of vocalizations in a cerebellar-specific dystonia mouse model. | Dystonia | 2026 | 42294485 | PubTator, text mining | PubMed |
| Immunogenetic HLA-DQ and IgG serological profiles in individuals with self-reported wheat/gluten sensitivity: a retrospective real-world evidence study. | Front Immunol | 2026 | 42266680 | PubTator, text mining | PubMed |
| Essential genetic testing in movement disorders - results from a Delphi study. | Parkinsonism Relat Disord | 2026 | 42202611 | PubTator, text mining | PubMed |
1 to 10 of 3,348
See all 3,348 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1861
GET https://conductscience.org/api/genes/v1/1861/patents?page=2