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Gene · 1861

TOR1A: torsin family 1 member A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TOR1A: torsin family 1 member A. Genes, record 1861. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1861

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Gene

Symbol
TOR1A
HGNC
Name
torsin family 1 member A
HGNC
NCBI Gene ID
1861
NCBI Gene
HGNC ID
HGNC:3098
HGNC
Ensembl
ENSG00000136827
NCBI Gene
Aliases
AMC5, DQ2, DYT1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O14656Torsin-1A3323Ensembl, GeneID, HGNC

Source UniProt

Patents42

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467248O14656Espacenet
EP 4650780 A22025-11-197000O14656Espacenet
EP 4641201 A22025-10-296875O14656Espacenet
JP 2025147176 A2025-10-0613653O14656Espacenet
JP 2025529142 A2025-09-047952O14656Espacenet
US 12371689 B22025-07-297952O14656Espacenet
JP 2025517969 A2025-06-126875O14656Espacenet
JP 2025517970 A2025-06-127000O14656Espacenet
JP 2025028160 A2025-02-2813653O14656Espacenet
KR 1020250010750 A2025-01-2113653O14656Espacenet

1 to 10 of 42

See all 42 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,368

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTOR1A papersNewest fiscal year
R01DK032083Multiple Autoantigens, Multiple Epitopes of Type 1 Diabetes272025
R01DK063158Role of Transglutaminase 2 in Celiac Sprue182025
R01DC011805Imaging genetics of laryngeal dystonia152025
P30DK017047Diabetes Research Center122025
R01DK108868Insulin specific T cell response shaped by diabetes protective MHC class II molecules102025
R01DK099317Islet-specific CD8 T cells in the pathogenesis of type 1 diabetes72025
P01AI042288Immune Function and the Progression to Type 1 Diabetes62025
R01NS058949Clinical, Genetic, and Cellular Consequences of Mutations In NA,K-ATPase ATP1A362025
R01GM105672The mechanism of ESCRT-mediated surveillance of the nuclear envelope barrier52025
T32DK063687Developing Pediatric Endocrinologist for the Future52025

1 to 10 of 1,368Source NIH's project files

See all 1,368 nih grants

Papers3,348

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Founder mutations in movement disorders: global distribution, molecular mechanisms, and clinical consequences-a scoping review.Neurogenetics202642825921PubTator, text miningPubMed
A Protective Haplotype in trans Modifies Penetrance and Severity of TOR1A Dystonia.medRxiv202642818409PubTator, text miningPubMed
[Genetic Dystonias].Medicina (B Aires)202642659549PubTator, text miningPubMed
Child Neurology: Early-Onset, Rapidly Progressive, and Refractory DYT-TOR1A Status Dystonicus.Neurology202642551000PubTator, text miningPubMed
Integrative chemical genetics platform identifies condensate modulators linked to neurological disorders.Mol Biol Cell202642418712PubTator, text miningPubMed
The Biological Fate of DBS Leads After 15 Years of Stimulation.Mov Disord Clin Pract202642321150PubTator, text miningPubMed
The genetic landscape of childhood-onset dystonia in a nationwide Turkish cohort: Clinical spectrum, molecular diagnostics, and therapeutic implications.Eur J Paediatr Neurol202642308683PubTator, text miningPubMed
Assessing vocal changes through spectral analyses of vocalizations in a cerebellar-specific dystonia mouse model.Dystonia202642294485PubTator, text miningPubMed
Immunogenetic HLA-DQ and IgG serological profiles in individuals with self-reported wheat/gluten sensitivity: a retrospective real-world evidence study.Front Immunol202642266680PubTator, text miningPubMed
Essential genetic testing in movement disorders - results from a Delphi study.Parkinsonism Relat Disord202642202611PubTator, text miningPubMed

1 to 10 of 3,348

See all 3,348 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1861

GET https://conductscience.org/api/genes/v1/1861/patents?page=2