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E2F1: E2F transcription factor 1

1 protein, 85 patents, 2 drugs, 0 trials, 7,124 NIH grants and 16,487 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolE2F1HGNC
NameE2F transcription factor 1HGNC
NCBI Gene ID1869NCBI Gene
HGNC IDHGNC:3113HGNC
EnsemblENSG00000101412NCBI Gene
AliasesE2F-1, RBAP1, RBBP3, RBP3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q01094Transcription factor E2F14378Ensembl, GeneID, HGNCUniProt

Patents 85

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4641202 A22025-10-295203Q01094Espacenet
JP 2025147176 A2025-10-0614904Q01094Espacenet
JP 2025521922 A2025-07-1070Q01094Espacenet
JP 2025509665 A2025-04-114Q01094Espacenet
JP 2025028160 A2025-02-2814904Q01094Espacenet
KR 1020250017231 A2025-02-045203Q01094Espacenet
KR 1020250010750 A2025-01-2114904Q01094Espacenet
KR 1020240156639 A2024-10-304Q01094Espacenet
JP 2024123008 A2024-09-105969Q01094Espacenet
JP 2024109657 A2024-08-1414743Q01094Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
EDIFOLIGIDECHEMBL2108316E2F inhibitorINHIBITORChEMBL
EDIFOLIGIDE SODIUMCHEMBL2109058E2F inhibitorINHIBITORChEMBL

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 7124

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1522,025NIH's project files
P30CA008748Cancer Center Support Grant662,025NIH's project files
P30CA016058Cancer Center Support Grant372,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant332,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant252,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant232,025NIH's project files
P50CA097186The Pacific Northwest Prostate Cancer SPORE222,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase202,025NIH's project files
P30CA047904Cancer Center Support Grant202,025NIH's project files
P30CA056036Translational Research in Cancer202,025NIH's project files

Papers 16487

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42814286PubTator, text miningPubMed
42811795PubTator, text miningPubMed
42811076PubTator, text miningPubMed
42803692PubTator, text miningPubMed
42800881PubTator, text miningPubMed
42799703PubTator, text miningPubMed
42770314PubTator, text miningPubMed
42760375PubTator, text miningPubMed
42759273PubTator, text miningPubMed
42758397PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license