Gene · 1871
E2F3: E2F transcription factor 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. E2F3: E2F transcription factor 3. Genes, record 1871. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1871
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O00716 | Transcription factor E2F3 | 465 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents42
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 44617 | O00716 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 14906 | O00716 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 27603 | O00716 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 14906 | O00716 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 14906 | O00716 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 27603 | O00716 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14745 | O00716 | Espacenet |
| US 11708396 B2 | 2023-07-25 | 2201 | O00716 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 27603 | O00716 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 26389 | O00716 | Espacenet |
1 to 10 of 42
See all 42 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,999
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | E2F3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 38 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 31 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 11 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 9 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 9 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 8 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 7 | 2025 |
| U54CA163068 | 2/2 Ponce Health Sciences University-Moffitt Cancer Center Partnership | 7 | 2025 |
| U54CA163071 | (1/2) Ponce Health Sciences University-Moffitt Cancer Center Partnership # | 7 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 6 | 2025 |
1 to 10 of 1,999Source NIH's project files
See all 1,999 nih grantsPapers3,808
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| DNA damage response associated miRNA dysregulation in Ataxia-telangiectasia. | Mol Biol Rep | 2026 | 42814286 | PubTator, text mining | PubMed |
| E2F3 amplification primes bladder cancer cells for premature mitosis. | Cancer Gene Ther | 2026 | 42773250 | PubTator, text mining | PubMed |
| Subtype-Dependent Transcriptional Coupling Between DNMT1 and E2F-Linked Proliferative Programs in Breast Cancer: A Dual-Cohort Transcriptomic Analysis. | J Cancer | 2026 | 42741635 | PubTator, text mining | PubMed |
| Serum Peptidomic Analysis in a Comparative Study of the Efficacy of Benjakul Remedy Versus Loratadine in Allergic Rhinitis Patients. | Int J Mol Sci | 2026 | 42653391 | PubTator, text mining | PubMed |
| Complement factor H in cancer biology: intracellular functions, tumor-host interactions, and systemic context. | Front Immunol | 2026 | 42592211 | PubTator, text mining | PubMed |
| Long non-coding RNA LOXL1 antisense RNA 1 promotes the malignancy of non-small cell lung cancer cells via modulating the microRNA-122-5p/E2F transcription factor 3 axis. | Mol Genet Genomics | 2026 | 42484731 | PubTator, text mining | PubMed |
| The diagnostic value and molecular mechanism of miR-199a-5p in recurrent spontaneous abortion. | J Assist Reprod Genet | 2026 | 42446609 | PubTator, text mining | PubMed |
| circ-E2F3 drives ovarian cancer progression via the miR-1305/STAT3 axis through modulation of ferroptosis. | Sci Rep | 2026 | 42373708 | PubTator, text mining | PubMed |
| Paclitaxel and triptolide impair MYC-driven cell cycle via suppressing chromatin reprogramming in ALDH1A3High pancreatic cancer. | Phytomedicine | 2026 | 42269181 | PubTator, text mining | PubMed |
| Correction: ELF1-mediated transactivation of METTL3/YTHDF2 promotes nucleus pulposus cell senescence via m6A-dependent destabilization of E2F3 mRNA in intervertebral disc degeneration. | Cell Death Discov | 2026 | 42215439 | PubTator, text mining | PubMed |
1 to 10 of 3,808
See all 3,808 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1871
GET https://conductscience.org/api/genes/v1/1871/patents?page=2