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Gene · 189

AGXT: alanine--glyoxylate aminotransferase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. AGXT: alanine--glyoxylate aminotransferase. Genes, record 189. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/189

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Gene

Symbol
AGXT
HGNC
Name
alanine--glyoxylate aminotransferase
HGNC
NCBI Gene ID
189
NCBI Gene
HGNC ID
HGNC:341
HGNC
Ensembl
ENSG00000172482
NCBI Gene
Aliases
AGT, AGT1, AGXT1, PH1, SPAT, SPT, Ser-PyrAT, TLH6
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P21549Alanine--glyoxylate aminotransferase39217Ensembl, GeneID, HGNC

Source UniProt

Patents48

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21139P21549Espacenet
JP 2026004568 A2026-01-1436951P21549Espacenet
EP 4641201 A22025-10-293710P21549Espacenet
JP 2025517969 A2025-06-123710P21549Espacenet
EP 4555087 A22025-05-2148P21549Espacenet
JP 2025062604 A2025-04-143753P21549Espacenet
JP 2024528659 A2024-07-3030P21549Espacenet
US 12006526 B22024-06-11244P21549Espacenet
JP 2024519469 A2024-05-1464P21549Espacenet
JP 2024026211 A2024-02-28244P21549Espacenet

1 to 10 of 48

See all 48 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,683

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAGXT papersNewest fiscal year
P01CA097132Sphingolipids in Cancer Biology and Therapy202025
P30CA008748Cancer Center Support Grant102025
P30CA016059Massey Cancer Center - Cancer Center Support Grant92025
P01CA018029Adult Leukemia Research Center72025
P30CA016672Cancer Center Support Grant72025
P30CA138313Medical University of South Carolina - Cancer Center Support Grant72025
ZIANS003129Molecular and Clinical Manifestations of Matrix and Aggregate Myopathies72025
P30DK020572Michigan Diabetes Research Center (MDRC)52025
P30DK020579Diabetes Research Center52025
R01DE016572Ceramide Signaling in the Regulation of Head & Neck Cancer Cell Death and Therapy52025

1 to 10 of 1,683Source NIH's project files

See all 1,683 nih grants

Papers3,768

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Electron-driven proton transfer behaviors in oxidative DNA lesion 8-oxoguanine: A computational study.Talanta202742407159PubTator, text miningPubMed
Data from the French Daily-Luma cohort suggest predictors of a lumasiran response.Kidney Int202642805337PubTator, text miningPubMed
Mutational Landscape of Primary Hyperoxaluria in Morocco: Update and Implications for Diagnosis.Genes (Basel)202642792949PubTator, text miningPubMed
Integrative Genomic and Transcriptomic Analysis Reveals Hypothesis-Generating Candidate Genes for Nephrolithiasis Susceptibility in Primary Hyperoxaluria.Nephrology (Carlton)202642775502PubTator, text miningPubMed
Ceramide 1-phosphate binding proteins: emerging regulators of cell physiology and disease.Biochem Cell Biol202642715607PubTator, text miningPubMed
Linker Histone H1 Phosphorylation Promotes DNA Damage Repair during Replication Stress.ACS Chem Biol202642690615PubTator, text miningPubMed
Primary Hyperoxaluria Type 1 Diagnosed After Kidney Transplantation in the Absence of Classical Features.Case Rep Nephrol202642670475PubTator, text miningPubMed
Multi-Omics Identification of Vasculogenic Mimicry-Associated Molecular Subtypes in Hepatocellular Carcinoma for Prognostic Stratification and Therapeutic Response Prediction.Cancers (Basel)202642588699PubTator, text miningPubMed
Case Report: A rare AGXT pathogenic variant associated with young-adult-onset end-stage kidney disease.Front Genet202642583563PubTator, text miningPubMed
Step-brothers in arms, SAGA and ATAC co-activator complexes, use different strategies.EMBO J202642581098PubTator, text miningPubMed

1 to 10 of 3,768

See all 3,768 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/189

GET https://conductscience.org/api/genes/v1/189/patents?page=2