Gene · 189
AGXT: alanine--glyoxylate aminotransferase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. AGXT: alanine--glyoxylate aminotransferase. Genes, record 189. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/189
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P21549 | Alanine--glyoxylate aminotransferase | 392 | 17 | Ensembl, GeneID, HGNC |
Source UniProt
Patents48
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 139 | P21549 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 36951 | P21549 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3710 | P21549 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3710 | P21549 | Espacenet |
| EP 4555087 A2 | 2025-05-21 | 48 | P21549 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3753 | P21549 | Espacenet |
| JP 2024528659 A | 2024-07-30 | 30 | P21549 | Espacenet |
| US 12006526 B2 | 2024-06-11 | 244 | P21549 | Espacenet |
| JP 2024519469 A | 2024-05-14 | 64 | P21549 | Espacenet |
| JP 2024026211 A | 2024-02-28 | 244 | P21549 | Espacenet |
1 to 10 of 48
See all 48 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,683
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | AGXT papers | Newest fiscal year |
|---|---|---|---|
| P01CA097132 | Sphingolipids in Cancer Biology and Therapy | 20 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 10 | 2025 |
| P30CA016059 | Massey Cancer Center - Cancer Center Support Grant | 9 | 2025 |
| P01CA018029 | Adult Leukemia Research Center | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA138313 | Medical University of South Carolina - Cancer Center Support Grant | 7 | 2025 |
| ZIANS003129 | Molecular and Clinical Manifestations of Matrix and Aggregate Myopathies | 7 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 5 | 2025 |
| P30DK020579 | Diabetes Research Center | 5 | 2025 |
| R01DE016572 | Ceramide Signaling in the Regulation of Head & Neck Cancer Cell Death and Therapy | 5 | 2025 |
1 to 10 of 1,683Source NIH's project files
See all 1,683 nih grantsPapers3,768
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Electron-driven proton transfer behaviors in oxidative DNA lesion 8-oxoguanine: A computational study. | Talanta | 2027 | 42407159 | PubTator, text mining | PubMed |
| Data from the French Daily-Luma cohort suggest predictors of a lumasiran response. | Kidney Int | 2026 | 42805337 | PubTator, text mining | PubMed |
| Mutational Landscape of Primary Hyperoxaluria in Morocco: Update and Implications for Diagnosis. | Genes (Basel) | 2026 | 42792949 | PubTator, text mining | PubMed |
| Integrative Genomic and Transcriptomic Analysis Reveals Hypothesis-Generating Candidate Genes for Nephrolithiasis Susceptibility in Primary Hyperoxaluria. | Nephrology (Carlton) | 2026 | 42775502 | PubTator, text mining | PubMed |
| Ceramide 1-phosphate binding proteins: emerging regulators of cell physiology and disease. | Biochem Cell Biol | 2026 | 42715607 | PubTator, text mining | PubMed |
| Linker Histone H1 Phosphorylation Promotes DNA Damage Repair during Replication Stress. | ACS Chem Biol | 2026 | 42690615 | PubTator, text mining | PubMed |
| Primary Hyperoxaluria Type 1 Diagnosed After Kidney Transplantation in the Absence of Classical Features. | Case Rep Nephrol | 2026 | 42670475 | PubTator, text mining | PubMed |
| Multi-Omics Identification of Vasculogenic Mimicry-Associated Molecular Subtypes in Hepatocellular Carcinoma for Prognostic Stratification and Therapeutic Response Prediction. | Cancers (Basel) | 2026 | 42588699 | PubTator, text mining | PubMed |
| Case Report: A rare AGXT pathogenic variant associated with young-adult-onset end-stage kidney disease. | Front Genet | 2026 | 42583563 | PubTator, text mining | PubMed |
| Step-brothers in arms, SAGA and ATAC co-activator complexes, use different strategies. | EMBO J | 2026 | 42581098 | PubTator, text mining | PubMed |
1 to 10 of 3,768
See all 3,768 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/189
GET https://conductscience.org/api/genes/v1/189/patents?page=2