ConductScience.org, home

Gene · 1890

TYMP: thymidine phosphorylase

11 sourcesgene-search-2026-11-11-0.1.0

Download JSON
Cite this record

ConductScience Library. TYMP: thymidine phosphorylase. Genes, record 1890. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/1890

On this page

Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
TYMP
HGNC
Name
thymidine phosphorylase
HGNC
NCBI Gene ID
1890
NCBI Gene
HGNC ID
HGNC:3148
HGNC
Ensembl
ENSG00000025708
NCBI Gene
Aliases
ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P19971Thymidine phosphorylase4824Ensembl, GeneID, HGNC

Source UniProt

Patents154

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191368P19971Espacenet
EP 4641201 A22025-10-291000P19971Espacenet
EP 4641202 A22025-10-294456P19971Espacenet
JP 2025517969 A2025-06-121000P19971Espacenet
JP 2025517970 A2025-06-121368P19971Espacenet
KR 1020250017231 A2025-02-044456P19971Espacenet
JP 2024123008 A2024-09-108688P19971Espacenet
JP 2024123008 A2024-09-108689P19971Espacenet
JP 2024123008 A2024-09-108690P19971Espacenet
US 11987821 B22024-05-211P19971Espacenet

1 to 10 of 154

See all 154 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
TIPIRACILCHEMBL235668Thymidine phosphorylase inhibitorINHIBITORChEMBL
TIPIRACIL HYDROCHLORIDECHEMBL65375Thymidine phosphorylase inhibitorINHIBITORChEMBL

Trials136

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07527858TIPIRACILPHASE2ClinicalTrials.gov
NCT07491159TIPIRACILPHASE1/PHASE2ClinicalTrials.gov
NCT07381764TIPIRACILPHASE2ClinicalTrials.gov
NCT07371871TIPIRACILClinicalTrials.gov
NCT07361003TIPIRACILPHASE3ClinicalTrials.gov
NCT07318389TIPIRACILEARLY_PHASE1ClinicalTrials.gov
NCT07286695TIPIRACILPHASE2ClinicalTrials.gov
NCT07280377TIPIRACILPHASE1/PHASE2ClinicalTrials.gov
NCT07270991TIPIRACILPHASE3ClinicalTrials.gov
NCT07261709TIPIRACILPHASE2ClinicalTrials.gov

1 to 10 of 136

See all 136 trials

NIH grants1,409

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)92025
ZIAES065078Molecular Characterization Of The Mitochondrial Dna Polymerase92025
P30CA008748Cancer Center Support Grant82025
P30CA016672Cancer Center Support Grant82025
P20GM103434West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)72025
P30CA013148Comprehensive Cancer Center Support Grant72025
U54GM104942West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health72025
P30CA013330Cancer Center Support Grant62025
P30CA012197Cancer Center Support Grant52025
P30CA016056Roswell Park Cancer Center Support Grant52025

1 to 10 of 1,409Source NIH's project files

See all 1,409 nih grants

Papers4,467

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42801117PubTator, text miningPubMed
42737617PubTator, text miningPubMed
42654731PubTator, text miningPubMed
42653666PubTator, text miningPubMed
42639076PubTator, text miningPubMed
42582771PubTator, text miningPubMed
42529052PubTator, text miningPubMed
42523220PubTator, text miningPubMed
42508297PubTator, text miningPubMed
42439544PubTator, text miningPubMed

1 to 10 of 4,467

See all 4,467 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1890

GET https://conductscience.org/api/genes/v1/1890/patents?page=2