Gene · 1894
ECT2: epithelial cell transforming 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ECT2: epithelial cell transforming 2. Genes, record 1894. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1894
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9H8V3 | Protein ECT2 | 914 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents29
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 10949 | Q9H8V3 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11348 | Q9H8V3 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5856 | Q9H8V3 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11348 | Q9H8V3 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10949 | Q9H8V3 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 5856 | Q9H8V3 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 6022 | Q9H8V3 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 6028 | Q9H8V3 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 27748 | Q9H8V3 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 130719 | Q9H8V3 | Espacenet |
1 to 10 of 29
See all 29 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants856
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ECT2 papers | Newest fiscal year |
|---|---|---|---|
| T32CA071341 | Cancer Cell Biology Training Program | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 4 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 4 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 4 | 2025 |
| R01DK064380 | Molecular Mechanisms Regulating Epithelial Cell Apical Polarity and Ciliogenesis | 4 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 3 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 3 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 3 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 3 | 2025 |
1 to 10 of 856Source NIH's project files
See all 856 nih grantsPapers1,404
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrative single-cell and machine learning analysis identifies a tumor doubling time-related prognostic signature and therapeutic targets in head and neck squamous cell carcinoma. | Transl Oncol | 2026 | 42492364 | PubTator, text mining | PubMed |
| PRKCI-ECT2 copy number gain promotes developmental reprogramming and metastatic competence in lung adenocarcinoma. | Cell Rep | 2026 | 42470637 | PubTator, text mining | PubMed |
| A preliminary study of ECT2 as a novel biomarker for assessing liver fibrosis and prognosis in biliary atresia. | Front Pediatr | 2026 | 42445574 | PubTator, text mining | PubMed |
| A HRH1-YAP1 feedback loop drives pancreatic cancer progression and predicts therapeutic response. | Oncol Lett | 2026 | 42383289 | PubTator, text mining | PubMed |
| Effects from combined exposure to arsenic and dichloromethane: in vitro expression of genotoxicity, transformation and metastatic potential for cholangiocarcinogenesis. | Chem Biol Interact | 2026 | 42379413 | PubTator, text mining | PubMed |
| Early induction of the Rho-GEF ECT2 drives MEK/ERK oncogenic signaling in pancreatic ductal adenocarcinoma. | Oncogene | 2026 | 42321532 | PubTator, text mining | PubMed |
| Identification and validation of prognostic genes related to centrosome amplification in multiple myeloma. | PeerJ | 2026 | 42261309 | PubTator, text mining | PubMed |
| A TRPM4-associated necrotic cell death signature for prognostic stratification in pancreatic cancer. | J Gastrointest Oncol | 2026 | 42169933 | PubTator, text mining | PubMed |
| Novel transcriptomic alterations in poorly differentiated endometrial carcinomas: evidence from South African women. | Front Oncol | 2026 | 41952686 | PubTator, text mining | PubMed |
| TBXA2R activates ERMs to drive motility, invasion, and metastatic colonization of TNBC cells. | Life Sci Alliance | 2026 | 41844278 | PubTator, text mining | PubMed |
1 to 10 of 1,404
See all 1,404 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1894
GET https://conductscience.org/api/genes/v1/1894/patents?page=2