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Gene · 1896

EDA: ectodysplasin A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EDA: ectodysplasin A. Genes, record 1896. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1896

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Gene

Symbol
EDA
HGNC
Name
ectodysplasin A
HGNC
NCBI Gene ID
1896
NCBI Gene
HGNC ID
HGNC:3157
HGNC
Ensembl
ENSG00000158813
NCBI Gene
Aliases
ECTD1, ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, HED1, ODT1, STHAGX1, TNLG7C, XHED, XLHED
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92838Ectodysplasin-A3913Ensembl, GeneID, HGNC

Source UniProt

Patents108

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025169942 A2025-11-14961Q92838Espacenet
JP 2025529142 A2025-09-041351Q92838Espacenet
US 12371689 B22025-07-291351Q92838Espacenet
US 12202870 B22025-01-2152Q92838Espacenet
KR 1020230146133 A2023-10-1851Q92838Espacenet
JP 2023535090 A2023-08-1552Q92838Espacenet
KR 1020230066552 A2023-05-1641Q92838Espacenet
US 11446398 B22022-09-2026581Q92838Espacenet
US 11400116 B22022-08-022359Q92838Espacenet
JP 2022524081 A2022-04-27129552Q92838Espacenet

1 to 10 of 108

See all 108 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,413

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEDA papersNewest fiscal year
P30EY016665Core Grant for Vision Research132025
R01HL076246Chemokines in healing myocardial infarction82025
R01HL085440Resolution of inflammation in healing myocardial infarcts82025
P30CA023108Cancer Center Support Grant72025
R35GM118026Mechanisms of Genome Integrity52025
R01DE021475Development Genetics of Tooth Number Variation in Sticklebacks42025
P30CA006927Comprehensive Cancer Center Program at Fox Chase32025
P30DK058404Molecular and Cellular Basis for Digestive Diseases32025
P30EY010572Ophthalmology Core Facility32025
R01EY032905NFAT and fibrosis in the trabecular meshwork32025

1 to 10 of 1,413Source NIH's project files

See all 1,413 nih grants

Papers2,602

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Mechanisms of Phenotypic Evolution from Molecules to Organisms: Integrating Evolutionary Biochemistry and Evolutionary Developmental Biology.Annu Rev Ecol Evol Syst202642751651PubTator, text miningPubMed
Selective advantages, selective mismatches, chronic inflammation, obesity, and type 2 diabetes: a new hypothesis to explain the effects of natural selection on genetic variation at the ectodysplasin A receptor locus.
BMJ Open Diabetes Res Care202642710936PubTator, text miningPubMed
How much sweating is enough? Predicting thermoregulatory capacity in patients with ectodermal dysplasia based on a minimal pilocarpine-induced sweat volume.Front Pediatr202642683232PubTator, text miningPubMed
Role of EDA Fibronectin and Toll-like Receptor 5 in the Development of the Tumor Microenvironment in Triple Negative Breast Cancer.Cancers (Basel)202642650004PubTator, text miningPubMed
The first report of hypohidrotic ectodermal dysplasia caused by a novel mutation and accompanied with pathological femoral neck fracture: A case report.Medicine (Baltimore)202642601715PubTator, text miningPubMed
The emergence of the ectodysplasin pathway.Open Life Sci202642453607PubTator, text miningPubMed
Cutaneous embryology: Physiological basis and clinical implications.J Eur Acad Dermatol Venereol202642403001PubTator, text miningPubMed
Whole exome sequencing uncovers key genetic variants in congenital tooth agenesis: an integrative omics approach.Gene202642336005PubTator, text miningPubMed
Case Report: Fatal pneumonia as a manifestation of X-linked hypohidrotic ectodermal dysplasia: clinical phenotype and genotype characterization of a novel EDA frameshift variant in a four-generation pedigree.
Front Pediatr202642317666PubTator, text miningPubMed
Retraction: Functional Study of Ectodysplasin-A Mutations Causing Non-Syndromic Tooth Agenesis.PLoS One202642308199PubTator, text miningPubMed

1 to 10 of 2,602

See all 2,602 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1896

GET https://conductscience.org/api/genes/v1/1896/patents?page=2