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Gene · 190

NR0B1: nuclear receptor subfamily 0 group B member 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NR0B1: nuclear receptor subfamily 0 group B member 1. Genes, record 190. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/190

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Gene

Symbol
NR0B1
HGNC
Name
nuclear receptor subfamily 0 group B member 1
HGNC
NCBI Gene ID
190
NCBI Gene
HGNC ID
HGNC:7960
HGNC
Ensembl
ENSG00000169297
NCBI Gene
Aliases
AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1, SRXY2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P51843Nuclear receptor subfamily 0 group B member 14701Ensembl, GeneID, HGNC

Source UniProt

Patents27

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-2910407P51843Espacenet
JP 2025147176 A2025-10-0615413P51843Espacenet
JP 2025517969 A2025-06-1210407P51843Espacenet
JP 2025081326 A2025-05-2749P51843Espacenet
JP 2025028160 A2025-02-2815413P51843Espacenet
KR 1020250010750 A2025-01-2115413P51843Espacenet
JP 2024109657 A2024-08-1415252P51843Espacenet
US 12024722 B22024-07-0291P51843Espacenet
US 11564998 B22023-01-316573P51843Espacenet
US 11446398 B22022-09-2058380P51843Espacenet

1 to 10 of 27

See all 27 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,087

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNR0B1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant162025
P30CA042014Cancer Center Support Grant162025
P40OD010440Caenorhabditis Genetics Center102025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant92025
R01DK062027Mechanisms of Adrenal Differentiation82025
P30CA016058Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant52025
P30DK020572Michigan Diabetes Research Center (MDRC)52025
P30DK020593Vanderbilt Diabetes Research Center52025
R01DK043140Mechanisms Leading to Adrenal Zonation52025

1 to 10 of 2,087Source NIH's project files

See all 2,087 nih grants

Papers3,637

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
How Ocean Acidification Makes Marine Fish Reproduction Vulnerable: Physiological Mechanisms and Ecosystem Consequences.Toxics202642797753PubTator, text miningPubMed
Xp21 contiguous gene deletion syndrome presenting as congenital adrenal hypoplasia: molecular diagnosis and clinical re-evaluation of a pedigree.Front Endocrinol (Lausanne)202642729112PubTator, text miningPubMed
PROFET predicts continuous gene expression dynamics from scRNA-seq data to elucidate heterogeneity of cancer treatment responses.Cell Syst202642664975PubTator, text miningPubMed
Development and Biological Evaluation of FL18-Based Novel Antimicrobial Peptide Constructs Against Bacterial Pathogens.ACS Omega202642662717PubTator, text miningPubMed
Clinical, hormonal, and genetic spectrum of cryptorchidism: a comprehensive evaluation of patients referred for pediatric endocrinological assessment.J Pediatr Endocrinol Metab202642638530PubTator, text miningPubMed
CMA-associated cellular state remodeling defines prognostic heterogeneity and identifies ARRDC3 as a protective functional gene in small cell lung cancer.Front Cell Dev Biol202642564958PubTator, text miningPubMed
Clinical challenges of an Xp21 contiguous gene deletion syndrome in a newborn and 15 months of follow-up - case report.Front Endocrinol (Lausanne)202642548444PubTator, text miningPubMed
Hepatic stearoyl-CoA desaturase deficiency ameliorates hyperglycemia through bile acid signaling in an insulin-independent manner.bioRxiv202642465393PubTator, text miningPubMed
NR0B1 Gene Variants as Rare Forms of Primary Adrenal Insufficiency in Children: Case Report and Narrative Review.Genes (Basel)202642353799PubTator, text miningPubMed
DAX-1 in sex determination and gonadal development: revisiting the anti-testis hypothesis.Endocr Rev202642322018PubTator, text miningPubMed

1 to 10 of 3,637

See all 3,637 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/190

GET https://conductscience.org/api/genes/v1/190/patents?page=2