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EDN1: endothelin 1

1 protein, 125 patents, 0 drugs, 0 trials, 9,228 NIH grants and 28,604 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolEDN1HGNC
Nameendothelin 1HGNC
NCBI Gene ID1906NCBI Gene
HGNC IDHGNC:3176HGNC
EnsemblENSG00000078401NCBI Gene
AliasesARCND3, ET1, HDLCQ7, PPET1, QMENCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P05305Endothelin-121217Ensembl, GeneID, HGNCUniProt

Patents 125

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910149P05305Espacenet
JP 2025147176 A2025-10-064541P05305Espacenet
JP 2025529142 A2025-09-046228P05305Espacenet
US 12371689 B22025-07-296228P05305Espacenet
JP 2025517970 A2025-06-1210149P05305Espacenet
JP 2025028160 A2025-02-284541P05305Espacenet
JP 2025019061 A2025-02-063P05305Espacenet
JP 2025013795 A2025-01-2815P05305Espacenet
KR 1020250010750 A2025-01-214541P05305Espacenet
US 12181474 B22024-12-3115P05305Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 9228

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
T32HL105324Hypertension and Cardiorenal Research Training Program402,025NIH's project files
P20GM121334Mississippi Center of Excellence in Perinatal Research, Phase 2262,025NIH's project files
R01HL060190Metabolic reprogramming of smooth muscle cells in pulmonary hypertension212,025NIH's project files
P30CA008748Cancer Center Support Grant182,025NIH's project files
P30CA016672Cancer Center Support Grant172,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award152,025NIH's project files
I01BX000347Cerebral Arteriole Structure/Function in Diabetic Ischemic Brain Injury132,025NIH's project files
U54GM115428Mississippi Center for Clinical and Translational Research132,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)122,025NIH's project files
P30DK036836Diabetes Research Center122,025NIH's project files

Papers 28604

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822897PubTator, text miningPubMed
42819474PubTator, text miningPubMed
42816964PubTator, text miningPubMed
42810538PubTator, text miningPubMed
42809538PubTator, text miningPubMed
42807193PubTator, text miningPubMed
42802951PubTator, text miningPubMed
42802640PubTator, text miningPubMed
42798440PubTator, text miningPubMed
42795536PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license