Gene · 1908
EDN3: endothelin 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EDN3: endothelin 3. Genes, record 1908. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1908
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P14138 | Endothelin-3 | 238 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents54
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 44971 | P14138 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 44973 | P14138 | Espacenet |
| JP 2025172884 A | 2025-11-26 | 1 | P14138 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6249 | P14138 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6012 | P14138 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 4545 | P14138 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 4546 | P14138 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6230 | P14138 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6230 | P14138 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6012 | P14138 | Espacenet |
1 to 10 of 54
See all 54 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,222
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EDN3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 11 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 8 | 2025 |
| R01HL086694 | From GWAS loci to blood pressure genes, variants & mechanisms - Renewal | 5 | 2025 |
| T32HL007208 | Integrated, Multidisciplinary Training in Cardiovascular Research | 4 | 2025 |
| ZIAHL006001 | Framingham Project/Levy | 4 | 2025 |
| I01BX000347 | Cerebral Arteriole Structure/Function in Diabetic Ischemic Brain Injury | 3 | 2025 |
| IK6BX004471 | BLR&D Research Career Scientist Award Application | 3 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| P30CA072720 | Cancer Center Support Grant | 3 | 2025 |
| P30DK036836 | Diabetes Research Center | 3 | 2025 |
1 to 10 of 1,222Source NIH's project files
See all 1,222 nih grantsPapers2,260
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Analysis of urinary kidney-specific cell-free DNA in preeclampsia. | PLoS One | 2026 | 42809538 | PubTator, text mining | PubMed |
| Analysis of the expression of genes encoding the endothelin signaling pathway in fetal, heathy, and diseased adult human heart using single-cell transcriptomics. | Can J Physiol Pharmacol | 2026 | 42753274 | PubTator, text mining | PubMed |
| 808 nm-excited highly-pure red upconversion emission from Er3+ in bi-perovskite Ca2ScSbO6 via Yb3+-mediated energy transfer. | Spectrochim Acta A Mol Biomol Spectrosc | 2026 | 42480485 | PubTator, text mining | PubMed |
| Rexiao Kuining decoction ameliorates ulcerative colitis by restoring immune homeostasis via the protein kinase C alpha-FMS-like tyrosine kinase 3 ligand axis: multi-omics evidence. | J Ethnopharmacol | 2026 | 42264446 | PubTator, text mining | PubMed |
Cumulative Reproductive Outcomes Across Three Embryo Transfer Cycles After Hysteroscopic Endometrial Polypectomy Using a Tissue Removal System in Infertile Women: A Single-Center Retrospective Cohort Study. | Diagnostics (Basel) | 2026 | 42122089 | PubTator, text mining | PubMed |
| Network pharmacology reveals lidocaine's modulation of proliferation and apoptosis in breast cancer cells: regulation of cellular lipid metabolism. | Arch Physiol Biochem | 2026 | 42102290 | PubTator, text mining | PubMed |
| EDNRB-dependent endothelin signaling reduces proliferation and promotes proneural-to-mesenchymal transition in gliomas. | Mol Oncol | 2026 | 42026941 | PubTator, text mining | PubMed |
| Abnormalities of liver sinusoidal endothelial cells in primary biliary cholangitis. | World J Exp Med | 2026 | 41883439 | PubTator, text mining | PubMed |
| Machine learning derived ORC6 as a hub biomarker for predicting tumor microenvironment, prognoses, and therapeutic responses in lung adenocarcinoma. | Transl Oncol | 2026 | 41875810 | PubTator, text mining | PubMed |
| A cis-regulatory mutation in the EDN3 promoter drives coordinated formation of comb and skin color in Anyi gray chickens. | Poult Sci | 2026 | 41850061 | PubTator, text mining | PubMed |
1 to 10 of 2,260
See all 2,260 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1908
GET https://conductscience.org/api/genes/v1/1908/patents?page=2