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Gene · 191

AHCY: adenosylhomocysteinase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. AHCY: adenosylhomocysteinase. Genes, record 191. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/191

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Gene

Symbol
AHCY
HGNC
Name
adenosylhomocysteinase
HGNC
NCBI Gene ID
191
NCBI Gene
HGNC ID
HGNC:343
HGNC
Ensembl
ENSG00000101444
NCBI Gene
Aliases
AdoHcyase, SAHH, adoHcyase
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P23526Adenosylhomocysteinase43210Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21303P23526Espacenet
JP 2026004568 A2026-01-1436674P23526Espacenet
EP 4650780 A22025-11-19395P23526Espacenet
EP 4641201 A22025-10-29276P23526Espacenet
EP 4641202 A22025-10-294327P23526Espacenet
JP 2025517969 A2025-06-12276P23526Espacenet
JP 2025517970 A2025-06-12395P23526Espacenet
JP 2025062604 A2025-04-142763P23526Espacenet
KR 1020250017231 A2025-02-044327P23526Espacenet
JP 2023521663 A2023-05-25302P23526Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,143

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAHCY papersNewest fiscal year
P30CA023168Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant62025
P30CA008748Cancer Center Support Grant52025
P30CA006927Comprehensive Cancer Center Program at Fox Chase42025
P30DK056350Nutrition Obesity Research Center (NORC)42025
R01GM117275Protein N-terminal Methylation Mechanisms and Inhibition42025
P30CA006516Dana-Farber/Harvard Cancer Center32025
P30ES010126UNC Center for Environmental Health and Susceptibility32025
P50AA022538Center for Alcohol Research in Epigenetics32025
R01AI127793Neisseria gonorrhoeae metal transporters that subvert nutritional immunity32025

1 to 10 of 1,143Source NIH's project files

See all 1,143 nih grants

Papers2,143

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Metabolic-cell-death gene trio predicts survival and cuproptosis sensitivity in colorectal cancer.J Gastrointest Oncol202642703393PubTator, text miningPubMed
Hydration at C5'-C6' double bond of adenosine substrates by S-adenosyl-L-homocysteine hydrolase.Nucleosides Nucleotides Nucleic Acids202642695797PubTator, text miningPubMed
Integrated bulk and single-cell transcriptomics unveil the role of AHCY in cell cycle regulation of endometrial cancer.Front Oncol202642694123PubTator, text miningPubMed
Distribution of luxS and production of autoinducer-2 among gut Bacteroidales.bioRxiv202642619800PubTator, text miningPubMed
S-Adenosyl-L-Homocysteine Hydrolase (SAHH): Structure, Function, and Applications.Biomolecules202642509803PubTator, text miningPubMed
Integrated proteomics and machine learning for identifying candidate serum biomarkers in acute myocardial infarction-complicated cardiogenic shock: a prospective exploratory study.Clin Proteomics202642477545PubTator, text miningPubMed
Disruption of methionine metabolism drives erythroid cell fate reprogramming by remodeling the H3K4me3 landscape.J Clin Invest202642446929PubTator, text miningPubMed
Nutrigenomic regulation of one-carbon metabolism and the circadian clock in health and disease.J Biochem202642383762PubTator, text miningPubMed
DZNep: A Methyltransferase Modulator for Disease Mitigation.Environ Mol Mutagen202642345323PubTator, text miningPubMed
Multifaceted anti-infective efficacy of Alstonia scholaris (Mizoram chemotype) against fungal, malarial, and intestinal helminth pathogens: in vitro validation and molecular docking insights.Vet World202642344326PubTator, text miningPubMed

1 to 10 of 2,143

See all 2,143 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/191

GET https://conductscience.org/api/genes/v1/191/patents?page=2