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Gene · 1947

EFNB1: ephrin B1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EFNB1: ephrin B1. Genes, record 1947. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1947

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Gene

Symbol
EFNB1
HGNC
Name
ephrin B1
HGNC
NCBI Gene ID
1947
NCBI Gene
HGNC ID
HGNC:3226
HGNC
Ensembl
ENSG00000090776
NCBI Gene
Aliases
CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P98172Ephrin-B13461Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445100P98172Espacenet
EP 4650780 A22025-11-19228P98172Espacenet
JP 2025529142 A2025-09-041362P98172Espacenet
US 12371689 B22025-07-291362P98172Espacenet
JP 2025517970 A2025-06-12228P98172Espacenet
JP 2025506727 A2025-03-1363P98172Espacenet
EP 4511052 A22025-02-2658P98172Espacenet
US 11446398 B22022-09-2027678P98172Espacenet
US 11400116 B22022-08-023041P98172Espacenet
JP 2022524081 A2022-04-27130649P98172Espacenet

1 to 10 of 61

See all 61 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,049

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEFNB1 papersNewest fiscal year
ZIABC010958Signaling Mechanisms of EphrinB1 in Cell Adhesion, Migration and Invasion92025
P30CA016672Cancer Center Support Grant72025
P30CA068485Cancer Center Support Grant52025
ZIABC010006Mechanisms of Cross-talk Between EphrinB and Alternate Signaling Pathways52025
R01DA022727Cell-Contact Mediated Mechanisms Assembling Synapses (R01DA022727)42025
P30CA008748Cancer Center Support Grant32025
P30DK058404Molecular and Cellular Basis for Digestive Diseases32025
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment32025
P30EY008126Core Grant in Vision Research32025
T32AI007647Training Program in Mechanisms of Virus-Host Interactions32025

1 to 10 of 1,049Source NIH's project files

See all 1,049 nih grants

Papers1,342

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Clinical and genetic features of syndromic craniosynostosis in 18 Chinese probands: novel candidate genes and phenotypes of known pathogenic genes.Front Genet202642609909PubTator, text miningPubMed
Elucidating the Activity of E-Lian Granule in Alleviating Chronic Atrophic Gastritis: Insights from Network Pharmacology, Molecular Docking, and Experimental Validation.Curr Comput Aided Drug Des202642576526PubTator, text miningPubMed
The middle cerebral artery early branches classification (MCA-EB): a novel imaging-based approach.Front Neurol202642488394PubTator, text miningPubMed
Host heterogeneity shapes clonal selection and organotropism in an extranodal lymphoma mouse model.Cell Death Dis202642431866PubTator, text miningPubMed
Physical interaction with Ephrin B1 promotes CXCR4 intracellular localization and oncogenic potential.Cell Mol Life Sci202642340382PubTator, text miningPubMed
Evidence-based classification of genes implicated in craniosynostosis disorders using the ClinGen curation framework.Genet Med202642059179PubTator, text miningPubMed
Clinical and Neurodevelopmental Course in a Case of EFNB1-Related Craniofrontonasal Syndrome With Unrepaired Craniosynostosis.Mol Genet Genomic Med202642026842PubTator, text miningPubMed
From brown to white: Brown adipose tissue endothelial cells whiten in culture conditions.Mol Metab202641831567PubTator, text miningPubMed
EPHA2-Ephrin-B1 cis-interaction drives an oncogenic reverse signaling, leading to the recurrence of oral cancer.Cell Commun Signal202641814365PubTator, text miningPubMed
Human milk oligosaccharides promote synaptogenesis and neurite outgrowth in human cortical organoids.Biochem Biophys Rep202641799697PubTator, text miningPubMed

1 to 10 of 1,342

See all 1,342 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1947

GET https://conductscience.org/api/genes/v1/1947/patents?page=2