Gene · 1948
EFNB2: ephrin B2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EFNB2: ephrin B2. Genes, record 1948. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1948
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P52799 | Ephrin-B2 | 333 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents91
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12655390 B2 | 2026-06-16 | 2 | P52799 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 19361 | P52799 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1363 | P52799 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1363 | P52799 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 19361 | P52799 | Espacenet |
| JP 2025069136 A | 2025-04-30 | 1 | P52799 | Espacenet |
| EP 4511052 A2 | 2025-02-26 | 60 | P52799 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 6007 | P52799 | Espacenet |
| JP 2023514611 A | 2023-04-06 | 114 | P52799 | Espacenet |
| US 11591576 B2 | 2023-02-28 | 114 | P52799 | Espacenet |
1 to 10 of 91
See all 91 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| SEPHB4-HSA | CHEMBL4298079 | Ephrin-B2 inhibitor | INHIBITOR |
Source ChEMBL
Trials13
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT04486781 | SEPHB4-HSA | PHASE2 | ClinicalTrials.gov | |
| NCT04091867 | SEPHB4-HSA | PHASE1 | ClinicalTrials.gov | |
| NCT04033432 | SEPHB4-HSA | PHASE2 | 2022-04-27 | ClinicalTrials.gov |
| NCT03993106 | SEPHB4-HSA | PHASE2 | ClinicalTrials.gov | |
| NCT03552796 | SEPHB4-HSA | PHASE1 | ClinicalTrials.gov | |
| NCT03519984 | SEPHB4-HSA | PHASE1 | ClinicalTrials.gov | |
| NCT03146871 | SEPHB4-HSA | PHASE2 | ClinicalTrials.gov | |
| NCT03049618 | SEPHB4-HSA | PHASE2 | 2025-10-22 | ClinicalTrials.gov |
| NCT02799485 | SEPHB4-HSA | PHASE2 | ClinicalTrials.gov | |
| NCT02767921 | SEPHB4-HSA | PHASE1 | ClinicalTrials.gov |
1 to 10 of 13
See all 13 trialsNIH grants1,967
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EFNB2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 9 | 2025 |
| R01DA022727 | Cell-Contact Mediated Mechanisms Assembling Synapses (R01DA022727) | 9 | 2025 |
| R01DE028529 | Tackling Treg mediated resistance to radiation and anti-PDL1 in HNSCC's | 8 | 2025 |
| T32AI007647 | Training Program in Mechanisms of Virus-Host Interactions | 7 | 2025 |
| ZIASC010355 | Angiogenesis and Tumor Growth | 7 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 6 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 6 | 2025 |
| ZIABC010782 | Study of the Roles of SDF1 and CXCR4 in Hematopoiesis | 6 | 2025 |
| K12CA086913 | Paul Calabresi Award in Clinical Oncology Research | 5 | 2025 |
1 to 10 of 1,967Source NIH's project files
See all 1,967 nih grantsPapers2,853
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Discovery of Quercetin as a Potential Entry Inhibitor of Nipah Virus: A Path Toward Antiviral Therapy. | Int J Mol Sci | 2026 | 42794455 | PubTator, text mining | PubMed |
| Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease. | Ann Clin Transl Neurol | 2026 | 42754972 | PubTator, text mining | PubMed |
| Nipah virus in the era of global connectivity: molecular evolution, transmission risk, and preparedness strategies. | Virus Genes | 2026 | 42732490 | PubTator, text mining | PubMed |
| Discovery of Sennoside A as a Natural O-GlcNAcase Inhibitor That Ameliorates Parkinson's Disease by Restoring EphrinB2 O-GlcNAcylation. | Research (Wash D C) | 2026 | 42718897 | PubTator, text mining | PubMed |
| Macrophages Drive Ferroptosis Resistance after Radiotherapy. | Cancer Commun (Lond) | 2026 | 42698964 | PubTator, text mining | PubMed |
| Role of Arteriogenesis Mechanism in the Remodeling of Choke Vessels in Delayed Multiterritory Perforator Flaps: A Protein-Based Perspective. | Ann Plast Surg | 2026 | 42554444 | PubTator, text mining | PubMed |
| New insight into RNA biomarkers in neuropathic pain: a clinician-neuroscientist roadmap to translational testing and treatment monitoring a clinical review. | Front Pain Res (Lausanne) | 2026 | 42534835 | PubTator, text mining | PubMed |
| Ensemble Docking, MD, and MM/PBSA Identify Flavonoids as Putative Modulators of EFNB2/B3-Nipah Virus G Interaction. | Int J Mol Sci | 2026 | 42511483 | PubTator, text mining | PubMed |
| The extracellular matrix in selective decussation of retinal ganglion cell axons: β2 laminins regulate the ipsilateral projection. | Dev Biol | 2026 | 42480735 | PubTator, text mining | PubMed |
| Identification and analysis of EphrinB2/EphB4 signaling pathway and angiogenesis related biomarkers in coronary artery disease based on bioinformatics. | J Cardiothorac Surg | 2026 | 42477815 | PubTator, text mining | PubMed |
1 to 10 of 2,853
See all 2,853 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1948
GET https://conductscience.org/api/genes/v1/1948/patents?page=2