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EGR1: early growth response 1

1 protein, 127 patents, 1 drug, 0 trials, 8,362 NIH grants and 14,658 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolEGR1HGNC
Nameearly growth response 1HGNC
NCBI Gene ID1958NCBI Gene
HGNC IDHGNC:3238HGNC
EnsemblENSG00000120738NCBI Gene
Aliases225, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZIF268, ZNF225NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P18146Early growth response protein 15435Ensembl, GeneID, HGNCUniProt

Patents 127

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026504811 A2026-02-1082P18146Espacenet
JP 2026502946 A2026-01-2735P18146Espacenet
JP 2026004568 A2026-01-1444647P18146Espacenet
EP 4650780 A22025-11-191010P18146Espacenet
EP 4642915 A22025-11-0582P18146Espacenet
EP 4642918 A12025-11-0535P18146Espacenet
EP 4641201 A22025-10-29706P18146Espacenet
EP 4641202 A22025-10-294404P18146Espacenet
JP 2025147176 A2025-10-0616033P18146Espacenet
KR 1020250128336 A2025-08-2735P18146Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BRIVOLIGIDECHEMBL4297228Early growth response protein 1 inhibitorINHIBITORChEMBL

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 8362

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant572,025NIH's project files
P30CA008748Cancer Center Support Grant272,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant212,025NIH's project files
P30ES006694Southwest Environmental Health Sciences Center202,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program182,025NIH's project files
P30CA016058Cancer Center Support Grant142,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant132,025NIH's project files
P30CA006973Regional Oncology Research Center122,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility122,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award122,025NIH's project files

Papers 14658

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42801082PubTator, text miningPubMed
42799656PubTator, text miningPubMed
42793251PubTator, text miningPubMed
42776409PubTator, text miningPubMed
42765067PubTator, text miningPubMed
42761908PubTator, text miningPubMed
42748574PubTator, text miningPubMed
42745198PubTator, text miningPubMed
42737510PubTator, text miningPubMed
42734444PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license