Gene · 1959
EGR2: early growth response 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EGR2: early growth response 2. Genes, record 1959. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1959
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P11161 | E3 SUMO-protein ligase EGR2 | 476 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents71
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 44650 | P11161 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 44653 | P11161 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 746 | P11161 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4410 | P11161 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 14918 | P11161 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 746 | P11161 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 14918 | P11161 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4410 | P11161 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 14918 | P11161 | Espacenet |
| WO 2024252368 A2 | 2024-12-12 | 32 | P11161 | Espacenet |
1 to 10 of 71
See all 71 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,415
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EGR2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| R01MH084894 | Function of GPCR heteromeric complexes in brain | 6 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 5 | 2025 |
| P01AI102853 | Molecular Basis for γδ T Lineage Specification | 4 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 4 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 4 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 4 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 4 | 2025 |
1 to 10 of 2,415Source NIH's project files
See all 2,415 nih grantsPapers3,476
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A Reproducible Transcriptomic Program of Neurofibroma-to-Malignant Peripheral Nerve Sheath Tumor Transformation. | Genes Chromosomes Cancer | 2026 | 42765715 | PubTator, text mining | PubMed |
| CpG content contributes to tissue-resident macrophage enhancer selection. | Nucleic Acids Res | 2026 | 42635130 | PubTator, text mining | PubMed |
| Identification of EGR2 and TGFB1 as Potential Immunoregulatory Biomarkers for Allergic Rhinitis: An Exploratory Bioinformatics and Pilot Validation Study. | Med Sci Monit | 2026 | 42543752 | PubTator, text mining | PubMed |
| EGR2 promotes vascular smooth muscle cell differentiation and proliferation in outward remodeling during arteriovenous fistula maturation. | Biochim Biophys Acta Mol Basis Dis | 2026 | 42526818 | PubTator, text mining | PubMed |
| Integrated 5-HT2A-TrkB and G protein signaling in serotonergic psychedelic responses. | Mol Psychiatry | 2026 | 42463904 | PubTator, text mining | PubMed |
| MAP1S limits autoimmune uveitis by suppressing Th17 differentiation through dual Control of the EGR2-LCN2 axis and autophagic flux. | Autophagy | 2026 | 42454709 | PubTator, text mining | PubMed |
| Abnormal Expression of has-miR-664b-5p in Allergic Rhinitis and Its Possible Impact on the Progression of the Disease. | Am J Rhinol Allergy | 2026 | 42434913 | PubTator, text mining | PubMed |
| Synthesis and Development of Novel Small-Molecule MEIS2 Inhibitors That Induce Cell Death in Breast Cancer Cells by Targeting the Homeobox Domain. | Pharmaceuticals (Basel) | 2026 | 42356499 | PubTator, text mining | PubMed |
| Study on diagnostic genes and immune microenvironment disorder in comorbid atherosclerosis and Alzheimer disease. | Medicine (Baltimore) | 2026 | 42332537 | PubTator, text mining | PubMed |
| Stearoyl-CoA desaturase 5 (SCD5) in lipid remodeling: From molecular control to pathophysiology. | J Lipid Res | 2026 | 42285304 | PubTator, text mining | PubMed |
1 to 10 of 3,476
See all 3,476 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1959
GET https://conductscience.org/api/genes/v1/1959/patents?page=2