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Gene · 1960

EGR3: early growth response 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EGR3: early growth response 3. Genes, record 1960. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1960

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Gene

Symbol
EGR3
HGNC
Name
early growth response 3
HGNC
NCBI Gene ID
1960
NCBI Gene
HGNC ID
HGNC:3240
HGNC
Ensembl
ENSG00000179388
NCBI Gene
Aliases
EGR-3, PILOT
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q06889Early growth response protein 33870Ensembl, GeneID, HGNC

Source UniProt

Patents45

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026504811 A2026-02-1083Q06889Espacenet
JP 2026502946 A2026-01-2736Q06889Espacenet
WO 2025237949 A12025-11-201Q06889Espacenet
EP 4650438 A12025-11-191Q06889Espacenet
EP 4650780 A22025-11-195153Q06889Espacenet
EP 4642915 A22025-11-0583Q06889Espacenet
EP 4642918 A12025-11-0536Q06889Espacenet
EP 4641202 A22025-10-294915Q06889Espacenet
JP 2025147176 A2025-10-0614919Q06889Espacenet
KR 1020250128336 A2025-08-2736Q06889Espacenet

1 to 10 of 45

See all 45 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,278

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEGR3 papersNewest fiscal year
P30CA016672Cancer Center Support Grant62025
R01DA038613Cocaine-induced mitochondrial mechanisms and molecular mediators in reward circuitry62025
P30CA006927Comprehensive Cancer Center Program at Fox Chase42025
P30CA008748Cancer Center Support Grant42025
P30CA046934University of Colorado Cancer Center Support Grant42025
P30CA010815Consolidated Basic Cancer Research Program32025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30CA023108Cancer Center Support Grant32025
P30CA047904Cancer Center Support Grant32025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center32025

1 to 10 of 1,278Source NIH's project files

See all 1,278 nih grants

Papers1,486

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrative Single-Cell and Spatial Transcriptomics Identifies CRIP1+ Prehypertrophic Chondrocytes as Inflammatory Hubs and a Valuable Diagnostic Biomarker for Osteoarthritis.Mediators Inflamm202642643032PubTator, text miningPubMed
Uncovering the Key Circuit FOSL2/FOS/EGR3/EGR1, Contributing to the Hyperexcitability of Excitatory Neurons in the Epileptic Temporal Cortex and Hippocampus.Int J Mol Sci202642196443PubTator, text miningPubMed
Transcription Factors in the Pathogenesis of Schizophrenia.Life (Basel)202642195329PubTator, text miningPubMed
Ailanthone targets the EGR3-SOCS2 regulatory pathway to suppress vasculogenic mimicry in prostate cancer.Biochem Pharmacol202641997257PubTator, text miningPubMed
c-MYC enhances transcription of the type 1 diabetes mellitus associated gene BATF3 via promoter binding.Sci Rep202641882260PubTator, text miningPubMed
STGNET: extending panel coverage in imaging-based spatial transcriptomics using deep generative adversarial networks.Brief Bioinform202641875024PubTator, text miningPubMed
Heterogeneity and prognostic significance of mast cell subsets in the tumor microenvironment of prostate cancer.Cancer Immunol Immunother202641874654PubTator, text miningPubMed
Olfactory cleft biopsy analysis of Alzheimer's disease pathobiology across disease stages.Nat Commun202641851126PubTator, text miningPubMed
Transcriptomics in Venous Leg Ulcers (VLU): A Systematic Review.Wound Repair Regen202641787822PubTator, text miningPubMed
Multi-Omics Data Reveal Estrogen-Driven Dysregulation and Stromal-Epithelial Signaling Alterations in Endometrial Polyps.FASEB J202641787252PubTator, text miningPubMed

1 to 10 of 1,486

See all 1,486 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1960

GET https://conductscience.org/api/genes/v1/1960/patents?page=2