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MLKL: mixed lineage kinase domain like pseudokinase
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Gene · 197259

Papers4,562

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

221 to 240 of 4,562

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TitleJournalYearPMIDFound bySource
Advances in neural mechanisms and magnetic resonance imaging biomarkers of aluminum exposure causing cognitive impairment.J Trace Elem Med Biol202641637841PubTator, text miningPubMed
Small-molecule modulators of the necroptotic pathway: A medicinal chemistry perspective.Eur J Med Chem202641633120PubTator, text miningPubMed
Inducible CD147 up-regulation boosts extended SARS-CoV-2 infection triggering severe COVID-19 independent of ACE2.Signal Transduct Target Ther202641629286PubTator, text miningPubMed
From Hit to Lead: Discovery of Novel Selective RIPK1 Inhibitor with Pyridoimidazole Scaffold for the Treatment of Autoimmune Diseases through Phenotypic Screening and Structural Optimization.J Med Chem202641628914PubTator, text miningPubMed
Neutrophil Extracellular Traps Induce PANoptosis and Inflammatory Responses in Fibroblast-Like Synoviocytes of Rheumatoid Arthritis.Int J Rheum Dis202641626711PubTator, text miningPubMed
Novel perspectives on extracellular vesicles in autoimmune diseases: immunogenicity, inflammation, and immune surveillance.J Clin Invest202641623176PubTator, text miningPubMed
Phospho-MLKL Upregulation in Immune-Mediated Necrotizing Myopathy: Implications for Disease Pathophysiology and Diagnosis.Neuropathology202641622430PubTator, text miningPubMed
A LNK-CBL-HNRPA2B1-GPX4 signaling axis mediates dopaminergic neuron vulnerability to ferroptosis in Parkinson's disease.Redox Biol202641616574PubTator, text miningPubMed
Endothelial MLKL Inhibition Reduces Hyperoxia-Induced Bronchopulmonary Dysplasia in Neonatal Mice.J Cell Mol Med202641608843PubTator, text miningPubMed
The soluble G protein of respiratory syncytial virus promotes viral dissemination via TLR2-mediated NLRP3 priming and pyroptosis.Npj Viruses202641593203PubTator, text miningPubMed
Spotted: RIPK3 and MLKL assembling necroptotic complexes.Open Biol202641592740PubTator, text miningPubMed
The evolutionary arms race on the Z-form-nucleic- acid-binding protein 1 front: endogenous Z-RNA as a self-danger signal.Mol Biomed202641591678PubTator, text miningPubMed
Complement contributes to ICI-triggered sialadenitis and predicts ICI efficacy.Cancer Immunol Immunother202641591573PubTator, text miningPubMed
SIRT1: An Emerging Role in Regulated Cell Death in Ischemic Stroke.CNS Neurol Disord Drug Targets202641582353PubTator, text miningPubMed
Identification of PANoptosis-related biomarkers in myocardial infarction via bioinformatics and single-cell analyses.Medicine (Baltimore)202641578497PubTator, text miningPubMed
RSV temporally reprograms apoptosis and pyroptosis to balance immune evasion and replication.Sci Adv202641576161PubTator, text miningPubMed
Vladimiria souliei alleviated ethanol induced gastric ulcer through inhibition of RIP1-RIP3-MLKL necrosome activation.Fitoterapia202641565122PubTator, text miningPubMed
A PNPLA3-NACC1-RIPK3 pathway mediates macrophage necroptosis and inflammation in MASLD.Hepatol Commun202641564367PubTator, text miningPubMed
Treating acute respiratory distress syndrome with a multifaceted nanomedicine: Inhibition of PANoptosis and enhancement of lung barrier integrity.Mater Today Bio202641560832PubTator, text miningPubMed
SLC25A39 binds and modulates PRDX1 to suppress ROS-induced necroptosis in hepatocellular carcinoma.Int Immunopharmacol202641558298PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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