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EIF4G1: eukaryotic translation initiation factor 4 gamma 1

1 protein, 32 patents, 0 drugs, 0 trials, 3,586 NIH grants and 6,270 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolEIF4G1HGNC
Nameeukaryotic translation initiation factor 4 gamma 1HGNC
NCBI Gene ID1981NCBI Gene
HGNC IDHGNC:3296HGNC
EnsemblENSG00000114867NCBI Gene
AliasesEIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18, p220NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q04637Eukaryotic translation initiation factor 4 gamma 11,59914Ensembl, GeneID, HGNCUniProt

Patents 32

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195079Q04637Espacenet
EP 4641201 A22025-10-294668Q04637Espacenet
JP 2025517969 A2025-06-124668Q04637Espacenet
JP 2025517970 A2025-06-125079Q04637Espacenet
JP 2024123008 A2024-09-106080Q04637Espacenet
JP 2024123008 A2024-09-106082Q04637Espacenet
JP 2023123507 A2023-09-05261Q04637Espacenet
JP 2023513211 A2023-03-3085Q04637Espacenet
US 11446398 B22022-09-2028777Q04637Espacenet
JP 2022524081 A2022-04-27131748Q04637Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3586

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant362,025NIH's project files
P30CA008748Cancer Center Support Grant232,025NIH's project files
ZIAHD001004Molecular Mechanisms of Translational Control172,025NIH's project files
R01CA080728Oncogenic Impact of eIF4E-dependent RNA Export in Cancer132,025NIH's project files
R01CA098571Molecular Mechanisms of eIF4E Mediated Transformation122,025NIH's project files
R35GM118173Chemical Synthesis of Complex Natural Products for Translational Science122,025NIH's project files
P30CA062203Cancer Center Support Grant112,025NIH's project files
P30CA016087Cancer Center Support Grant102,025NIH's project files
R01GM056927Control of Translation in Herpesvirus Infected Cells - Resubmission - 1102,025NIH's project files
P01CA125066Discovery of Anticancer Agents of Diverse Natural Origin92,025NIH's project files

Papers 6270

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42762359PubTator, text miningPubMed
42754366PubTator, text miningPubMed
42681522PubTator, text miningPubMed
42656030PubTator, text miningPubMed
42619987PubTator, text miningPubMed
42615421PubTator, text miningPubMed
42501872PubTator, text miningPubMed
42467756PubTator, text miningPubMed
42449070PubTator, text miningPubMed
42418312PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license