Gene · 1982
EIF4G2: eukaryotic translation initiation factor 4 gamma 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EIF4G2: eukaryotic translation initiation factor 4 gamma 2. Genes, record 1982. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1982
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P78344 | Eukaryotic translation initiation factor 4 gamma 2 | 907 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents16
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2020043864 A1 | 2020-03-05 | 1186 | P78344 | Espacenet |
| EP 3585909 A1 | 2020-01-01 | 236 | P78344 | Espacenet |
| KR 1020190126812 A | 2019-11-12 | 236 | P78344 | Espacenet |
| WO 2015174544 A | 2015-11-19 | 52 | P78344 | Espacenet |
| US 8586006 B2 | 2013-11-19 | 471 | P78344 | Espacenet |
| EP 2607900 A1 | 2013-06-26 | 1356 | P78344 | Espacenet |
| WO 2011027308 A1 | 2011-03-10 | 224 | P78344 | Espacenet |
| WO 2011027310 A1 | 2011-03-10 | 224 | P78344 | Espacenet |
| WO 2011027311 A2 | 2011-03-10 | 224 | P78344 | Espacenet |
| US 7867724 B2 | 2011-01-11 | 5 | P78344 | Espacenet |
1 to 10 of 16
See all 16 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants941
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EIF4G2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| K12CA215110 | YALE CANCER CENTER CALABRESI IMMUNO-ONCOLOGY TRAINING PROGRAM | 3 | 2025 |
| P20GM103418 | Kansas IDeA Network of Biomedical Research Excellence 5 | 3 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 3 | 2025 |
| R01CA142861 | Renewal: HPV and the DNA Damage Response | 3 | 2025 |
| R01HL164584 | uORF-mediated Translational Control of Cardiac Transcription Factor Expression | 3 | 2025 |
| R35GM119735 | Regulatory roles for the Integrator complex and circular RNAs | 3 | 2025 |
1 to 10 of 941Source NIH's project files
See all 941 nih grantsPapers1,382
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Biosynthesis of Complex Phenazines Involves Dimerization and Amination Catalyzed by a Versatile Nuclear Transport Factor 2‑like Superfamily Protein. | JACS Au | 2026 | 42819288 | PubTator, text mining | PubMed |
| Local translation couples synaptic activity to mitochondrial adaptation in dendrites. | bioRxiv | 2026 | 42779733 | PubTator, text mining | PubMed |
| Splicing dependency between EIF4G2 introns is mediated by exon definition and relies on a downstream splicing event. | J Biol Chem | 2026 | 42364809 | PubTator, text mining | PubMed |
| The role of RNA modifications in cancer translational control. | RNA Biol | 2026 | 42343618 | PubTator, text mining | PubMed |
| eIF4G2-Dependent Translation Restrains Pancreatic Cancer Progression. | Cancer Res | 2026 | 42202060 | PubTator, text mining | PubMed |
| Translation factor eIF4G2 directs CD8+ T cell lineage commitment by selectively enabling the IL-7 receptor response. | iScience | 2026 | 41940334 | PubTator, text mining | PubMed |
| A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia. | Nat Commun | 2026 | 41916975 | PubTator, text mining | PubMed |
| eIF4G2-dependent translation restrains pancreatic cancer progression. | bioRxiv | 2026 | 41890118 | PubTator, text mining | PubMed |
| PRRC2A, PRRC2B and PRRC2C are Stress Granule Proteins that Promote Translation Through Association with the eIF3 complex. | bioRxiv | 2026 | 41808986 | PubTator, text mining | PubMed |
| RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets. | MedComm (2020) | 2026 | 41756253 | PubTator, text mining | PubMed |
1 to 10 of 1,382
See all 1,382 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1982
GET https://conductscience.org/api/genes/v1/1982/patents