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Gene · 1997

ELF1: E74 like ETS transcription factor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ELF1: E74 like ETS transcription factor 1. Genes, record 1997. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1997

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Gene

Symbol
ELF1
HGNC
Name
E74 like ETS transcription factor 1
HGNC
NCBI Gene ID
1997
NCBI Gene
HGNC ID
HGNC:3316
HGNC
Ensembl
ENSG00000120690
NCBI Gene
Aliases
EFTUD1, RIA1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P32519ETS-related transcription factor Elf-16191Ensembl, GeneID, HGNC

Source UniProt

Patents46

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191006P32519Espacenet
EP 4641201 A22025-10-29704P32519Espacenet
JP 2025147176 A2025-10-0614922P32519Espacenet
JP 2025521922 A2025-07-1052P32519Espacenet
JP 2025517969 A2025-06-12704P32519Espacenet
JP 2025517970 A2025-06-121006P32519Espacenet
JP 2025028160 A2025-02-2814922P32519Espacenet
KR 1020250010750 A2025-01-2114922P32519Espacenet
JP 2024109657 A2024-08-1414761P32519Espacenet
JP 2024506208 A2024-02-09100P32519Espacenet

1 to 10 of 46

See all 46 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,409

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleELF1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant102025
R01AI049954Gene Transcription in SLE72025
P30CA042014Cancer Center Support Grant62025
P30CA076292Moffitt Cancer Center Support Grant52025
ZIABC010013Molecular Studies of Cellular Cytotoxicity52025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)42025
P30CA016056Roswell Park Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)42025
P30DK017047Diabetes Research Center42025
T32HG000044Institutional Training Grant in Genome Science42025

1 to 10 of 1,409Source NIH's project files

See all 1,409 nih grants

Papers1,339

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification and mechanistic investigation of novel biomarkers for diabetic retinopathy through hypoxia- and cuproptosis-associated gene analysis.PLoS One202642789564PubTator, text miningPubMed
METTL3 Promotes the Growth of Triple-Negative Breast Cancer Cells by Modulating Ferroptosis-Related Oxidative Stress via the ELF1/GPX4 Axis.Asia Pac J Clin Oncol202642706600PubTator, text miningPubMed
Clonal evolution and stromal crosstalk drive an invasive epithelial program in bladder cancer.Front Cell Dev Biol202642516298PubTator, text miningPubMed
Molecular basis of UV lesion binding and repair inhibition by ETS-family transcription factors.Nucleic Acids Res202642500821PubTator, text miningPubMed
G3BP2 confers venetoclax resistance by stabilizing ELF1-mediated MCL1 transcription in acute myeloid leukemia.Leukemia202642477086PubTator, text miningPubMed
EXPRESSION OF CONCERN: An Upstream Open Reading Frame Regulates Vasculogenic Mimicry of Glioma via ZNRD1-AS1/miR-499a-5p/ELF1/EMI1 Pathway.J Cell Mol Med202642374998PubTator, text miningPubMed
Intracellular lipid droplets positively regulate the dormancy of colorectal cancer cells depending on ELF1-ACSL5 signaling.J Exp Clin Cancer Res202642277938PubTator, text miningPubMed
Targeting the ELF1/EGFR/ERK positive feedback loop overcomes resistance to androgen receptor inhibition in AR-Vs positive prostate cancer.Neoplasia202642263596PubTator, text miningPubMed
Correction: ELF1-mediated transactivation of METTL3/YTHDF2 promotes nucleus pulposus cell senescence via m6A-dependent destabilization of E2F3 mRNA in intervertebral disc degeneration.Cell Death Discov202642215439PubTator, text miningPubMed
m5C RNA methylation is dysregulated by oncogenic herpesviruses via c-Myc signaling to counteract host antiviral factors.Nucleic Acids Res202641873763PubTator, text miningPubMed

1 to 10 of 1,339

See all 1,339 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1997

GET https://conductscience.org/api/genes/v1/1997/patents?page=2