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Gene · 1999

ELF3: E74 like ETS transcription factor 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ELF3: E74 like ETS transcription factor 3. Genes, record 1999. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1999

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Gene

Symbol
ELF3
HGNC
Name
E74 like ETS transcription factor 3
HGNC
NCBI Gene ID
1999
NCBI Gene
HGNC ID
HGNC:3318
HGNC
Ensembl
ENSG00000163435
NCBI Gene
Aliases
EPR-1, ERT, ESE-1, ESX
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P78545ETS-related transcription factor Elf-33711Ensembl, GeneID, HGNC

Source UniProt

Patents39

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444629P78545Espacenet
JP 2026004568 A2026-01-1444630P78545Espacenet
JP 2026004568 A2026-01-1444631P78545Espacenet
EP 4641201 A22025-10-297738P78545Espacenet
JP 2025147176 A2025-10-0614924P78545Espacenet
JP 2025517969 A2025-06-127738P78545Espacenet
JP 2025028160 A2025-02-2814924P78545Espacenet
KR 1020250010750 A2025-01-2114924P78545Espacenet
JP 2024109657 A2024-08-1414763P78545Espacenet
US 11446398 B22022-09-2026446P78545Espacenet

1 to 10 of 39

See all 39 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,571

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleELF3 papersNewest fiscal year
P30CA008748Cancer Center Support Grant152025
P30CA016672Cancer Center Support Grant152025
P30CA046934University of Colorado Cancer Center Support Grant82025
UL1TR001881UCLA Clinical and Translational Science Institute52025
P30CA016086Cancer Center Support Grant42025
P30CA036727Buffett Cancer Center Support Grant42025
P30CA091842Cancer Center Support Grant42025
P30DK034989Yale Liver Center42025
UL1TR001863Yale Clinical and Translational Science Award42025
P30CA016056Roswell Park Cancer Center Support Grant32025

1 to 10 of 1,571Source NIH's project files

See all 1,571 nih grants

Papers2,176

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Heterogeneous Radioimmunotherapy for Bulky Tumors: A Phase 1 Trial for Advanced Non-Small Cell Lung Cancer.Adv Radiat Oncol202642824609PubTator, text miningPubMed
Oral Actinobacteria sense and defend against parasitic epibionts.bioRxiv202642818358PubTator, text miningPubMed
Mapping Mutations and Signaling Network Interactions to Guide Precision Therapy in Gallbladder Cancer.Cancer Rep (Hoboken)202642817222PubTator, text miningPubMed
Episodic Future Thinking: A Behavioral Intervention to Promote Weight Loss in Breast Cancer Survivors (Alliance A21-Pilot10).JCO Oncol Adv202642808090PubTator, text miningPubMed
A canonical role of SMAD4 in safeguarding 3D genome architecture to suppress lung tumorigenesis.Oncogene202642760353PubTator, text miningPubMed
Target Antigen Identification for Antibody Drug Conjugate Therapy in Biliary Tract Cancer.Clin Cancer Res202642720429PubTator, text miningPubMed
A reproducible epithelial transcriptional state combines interferon-associated and secretory programs in pancreatic ductal adenocarcinoma.Front Genet202642656570PubTator, text miningPubMed
Integrative multi-omics analysis identifies an enhancer-driven ELF3-CLDN4 regulatory axis that shapes an immunosuppressive microenvironment and predicts prognosis in high-grade serous ovarian cancer.Gene202642624178PubTator, text miningPubMed
Construction and validation of a nomogram for the diagnosis of postmenopausal osteoporosis.Mol Med Rep202642596822PubTator, text miningPubMed
Super enhancer-driven transcriptional reprogramming promotes abiraterone resistance via neuroendocrine transition and ferroptosis evasion in castration-resistant prostate cancer.Oncogene202642527507PubTator, text miningPubMed

1 to 10 of 2,176

See all 2,176 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1999

GET https://conductscience.org/api/genes/v1/1999/patents?page=2