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Gene · 2000

ELF4: E74 like ETS transcription factor 4

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ELF4: E74 like ETS transcription factor 4. Genes, record 2000. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2000

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Gene

Symbol
ELF4
HGNC
Name
E74 like ETS transcription factor 4
HGNC
NCBI Gene ID
2000
NCBI Gene
HGNC ID
HGNC:3319
HGNC
Ensembl
ENSG00000102034
NCBI Gene
Aliases
AIFBL2, ELFR, MEF
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99607ETS-related transcription factor Elf-46630Ensembl, GeneID, HGNC

Source UniProt

Patents27

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444633Q99607Espacenet
JP 2026004568 A2026-01-1444634Q99607Espacenet
EP 4650780 A22025-11-194745Q99607Espacenet
JP 2025147176 A2025-10-0614925Q99607Espacenet
JP 2025517970 A2025-06-124745Q99607Espacenet
JP 2025028160 A2025-02-2814925Q99607Espacenet
KR 1020250010750 A2025-01-2114925Q99607Espacenet
JP 2024109657 A2024-08-1414764Q99607Espacenet
JP 2023554441 A2023-12-2739Q99607Espacenet
KR 1020230128488 A2023-09-0518Q99607Espacenet

1 to 10 of 27

See all 27 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,476

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleELF4 papersNewest fiscal year
P30CA008748Cancer Center Support Grant142025
P30CA016672Cancer Center Support Grant112025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant52025
U19AI089992Immune signatures of vaccine responses in vulnerable populations52025
P30CA016058Cancer Center Support Grant32025
P30CA016086Cancer Center Support Grant32025
P30CA047904Cancer Center Support Grant32025
P01CA018029Adult Leukemia Research Center22025
P30AI050410The University of North Carolina Center for AIDS Research22025
P30CA006516Dana-Farber/Harvard Cancer Center22025

1 to 10 of 1,476Source NIH's project files

See all 1,476 nih grants

Papers1,590

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Diagnostic evaluation of an EF1α RT-qPCR assay for RNA quality control in IPNV detection.J Virol Methods202742764132PubTator, text miningPubMed
A truncating ELF4 variant in a pediatric patient with autoinflammatory disease and cell type-specific immune alterations.Front Immunol202642769205PubTator, text miningPubMed
Genomic insights of invasive M1UK Group A Streptococci in Greece, 2019-2024.Infect Genet Evol202642759865PubTator, text miningPubMed
Quercetin Restores Antiviral Innate Immunity by Blocking BVDV Npro-Hsp70-Mediated ELF4 Degradation.J Agric Food Chem202642554809PubTator, text miningPubMed
Gram-positive oral bacteria as reservoirs of transferable antimicrobial resistance genes in dentistry.J Conserv Dent Endod202642549467PubTator, text miningPubMed
Integrative multi-omics and single-cell analysis identifies EGFR pathway activation and metabolic reprogramming as potential synthetic lethal vulnerabilities in resistance to the FGFR inhibitor AZD4547.
J Transl Med202642351126PubTator, text miningPubMed
Early-life carriage and antibiotic resistance of Streptococcus pneumoniae in infants from Sierra Leone.Front Microbiol202642254515PubTator, text miningPubMed
A novel ELF4 gene variant disrupts T and NK cell function in a patient with immune thrombocytopenia (ITP).Inflamm Res202642151449PubTator, text miningPubMed
Genomic and phenotypic characterization of a multidrug-resistant Streptococcus pneumoniae 19 F ST320 isolate from a pediatric SARS-CoV-2 case in Yogyakarta, Indonesia.Sci Rep202642031823PubTator, text miningPubMed
Identifying ICAM-1 as a Therapeutic Target for Cytokine Storm in Human Macrophages Through Integrative Bioinformatics Approaches.Molecules202641976154PubTator, text miningPubMed

1 to 10 of 1,590

See all 1,590 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2000

GET https://conductscience.org/api/genes/v1/2000/patents?page=2