ConductScience.org, home

Gene · 200315

APOBEC3A: apolipoprotein B mRNA editing enzyme catalytic subunit 3A

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. APOBEC3A: apolipoprotein B mRNA editing enzyme catalytic subunit 3A. Genes, record 200315. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/200315

On this page

Gene

Symbol
APOBEC3A
HGNC
Name
apolipoprotein B mRNA editing enzyme catalytic subunit 3A
HGNC
NCBI Gene ID
200315
NCBI Gene
HGNC ID
HGNC:17343
HGNC
Ensembl
ENSG00000128383
NCBI Gene
Aliases
A3A, ARP3, PHRBN, bK150C2.1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P31941DNA dC->dU-editing enzyme APOBEC-3A19912Ensembl, GeneID, HGNC

Source UniProt

Patents358

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4828972 A12026-10-2831P31941Espacenet
WO 2026213541 A12026-10-083P31941Espacenet
EP 4809080 A12026-09-2382P31941Espacenet
JP 2026525611 A2026-07-3163P31941Espacenet
JP 2026525611 A2026-07-3176P31941Espacenet
JP 2026525612 A2026-07-31496P31941Espacenet
JP 2026525612 A2026-07-31509P31941Espacenet
EP 4777618 A12026-07-2231P31941Espacenet
JP 2026116287 A2026-07-09276P31941Espacenet
EP 4762095 A12026-06-2431P31941Espacenet

1 to 10 of 358

See all 358 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,523

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAPOBEC3A papersNewest fiscal year
P01CA234228APOBEC Mutagenesis in Cancer372025
P30CA008748Cancer Center Support Grant262025
T32AI083196Minnesota Training Program in Virology202025
T32CA009138Molecular, Genetic and Cellular Targets of Cancer Training Program172025
R37CA252081Molecular Mechanisms of APOBEC-Induced Mutagenesis in Cancer132025
P30CA016672Cancer Center Support Grant112025
R35GM118047Structural studies of viral replication and invasion112025
RM1HG009490Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease102025
P30CA062203Cancer Center Support Grant92025
R01AI150524Structural Basis of APOBEC Functions and HIV Restriction92025

1 to 10 of 1,523Source NIH's project files

See all 1,523 nih grants

Papers1,983

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
APOBEC3 activity and DNA polymerase-ε deficiency are associated with distinct IDH1 R132 hotspot mutations.Mol Oncol202642717521PubTator, text miningPubMed
Motif-centered analyses reveal universal and tissue-specific mutagenic mechanisms operating in the human body.NAR Cancer202642707399PubTator, text miningPubMed
pgRNA-m6A levels associate with HBV replication and liver function.Epigenetics202642703000PubTator, text miningPubMed
Fluorescence polarization-based fragment screen identifies inhibitors of APOBEC3A and APOBEC3B.bioRxiv202642620011PubTator, text miningPubMed
Distinct repair processes produce APOBEC-induced deletions, tandem substitutions, and complex mutations in yeast and human cells.Proc Natl Acad Sci U S A202642520125PubTator, text miningPubMed
Break-induced replication forms long mutable single-strand DNA during meiosis.Nat Commun202642323311PubTator, text miningPubMed
Zinc finger protein ZBTB7A suppresses hepatitis B virus replication by attenuating FXRα-mediated HBV transcription and lowering covalently closed circular DNA levels.Antiviral Res202642320751PubTator, text miningPubMed
Squamous-state excursions activate APOBEC3A in cancer.bioRxiv202642244601PubTator, text miningPubMed
Establishment and Performance Evaluation of a Multiplexed TET2-APOBEC-Mediated cfDNA Methylation Detection Workflow Using qPCR and dPCR Readouts.J Pers Med202642188364PubTator, text miningPubMed
Enhanced TLR7-induced interferon responses in women living with HIV.Front Immunol202642093980PubTator, text miningPubMed

1 to 10 of 1,983

See all 1,983 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/200315

GET https://conductscience.org/api/genes/v1/200315/patents?page=2