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Gene · 201163

FLCN: folliculin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FLCN: folliculin. Genes, record 201163. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/201163

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Gene

Symbol
FLCN
HGNC
Name
folliculin
HGNC
NCBI Gene ID
201163
NCBI Gene
HGNC ID
HGNC:27310
HGNC
Ensembl
ENSG00000154803
NCBI Gene
Aliases
BHD, DENND8B, FLCL, MGC17998, MGC23445
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8NFG4Folliculin5794Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-193246Q8NFG4Espacenet
EP 4641201 A22025-10-292824Q8NFG4Espacenet
JP 2025517969 A2025-06-122824Q8NFG4Espacenet
JP 2025517970 A2025-06-123246Q8NFG4Espacenet
JP 2024123008 A2024-09-106278Q8NFG4Espacenet
US 11725026 B22023-08-1541Q8NFG4Espacenet
US 11446398 B22022-09-2032482Q8NFG4Espacenet
JP 2022524081 A2022-04-27135453Q8NFG4Espacenet
US 10501513 B22019-12-106278Q8NFG4Espacenet
JP 2017197545 A2017-11-0230979Q8NFG4Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants954

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFLCN papersNewest fiscal year
ZIABC011028Clinical Studies of the Molecular Genetic Basis of Kidney Cancer562025
ZIABC011043Molecular Therapeutics of Kidney Cancer: MET Gene and BHD Gene452025
ZIDBC011089Clinical Nursing and Data Management Core412025
ZIABC011038Molecular Therapeutics of Kidney Cancer: VHL Gene and Fumarate Hydratase Gene392025
P30CA008748Cancer Center Support Grant242025
ZICBC011044Tissue Processing-Sequencing Facility202025
P30CA016672Cancer Center Support Grant142025
ZIABC010696Study of Hereditary Renal and Other Familial Syndromes122025
ZIESC000853Translational Surgical Pathology102025
ZIABC011405microRNA Profiling in the Spectrum of Kidney Tumors82025

1 to 10 of 954Source NIH's project files

See all 954 nih grants

Papers1,937

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A TBK1/ULK1 signalling axis couples lysosomal stress to TFEB activation.Nature202642816627PubTator, text miningPubMed
Birt-Hogg-Dubé syndrome: From molecular mechanisms to emerging systemic therapeutic strategies.Med Clin (Barc)202642810013PubTator, text miningPubMed
FLCN Multi-Exon Deletion in a Chihuahua With Renal Cysts and Nodular Dermatofibrosis.Anim Genet202642808806PubTator, text miningPubMed
Disentangling the Cellular Composition of FLCN-Mutated Tumors in Birt-Hogg-Dubé Syndrome by Spatial Transcriptomics.Mod Pathol202642754233PubTator, text miningPubMed
From Guidelines to Practice: Pilot Implementation and Analytical Boundaries of a Focused ADPKD-Spectrum Gene Panel.Diagnostics (Basel)202642739200PubTator, text miningPubMed
Advanced Imaging Techniques for Early in-Vivo Discrimination of Fibrofolliculomas in Birt-Hogg-Dubé Syndrome.Skin Res Technol202642730490PubTator, text miningPubMed
An Underrecognized Cause of Recurrent Spontaneous Pneumothorax: Birt-Hogg-Dubé Syndrome With Isolated Pulmonary Manifestation.Respirol Case Rep202642719447PubTator, text miningPubMed
A Case of Birt-Hogg-Dubé Syndrome: A Rare but Essential Diagnosis to Consider.Fed Pract202642713334PubTator, text miningPubMed
[Birt-Hogg-Dubé syndrome-associated renal tumors: a clinicopathological and molecular genetic analysis of ten cases].Zhonghua Bing Li Xue Za Zhi202642706109PubTator, text miningPubMed
Exercise-associated epigenetic remodeling and TCR repertoire dynamics in Lynch syndrome carriers.iScience202642701426PubTator, text miningPubMed

1 to 10 of 1,937

See all 1,937 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/201163

GET https://conductscience.org/api/genes/v1/201163/patents?page=2