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Gene · 2016

EMX1: empty spiracles homeobox 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EMX1: empty spiracles homeobox 1. Genes, record 2016. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2016

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Gene

Symbol
EMX1
HGNC
Name
empty spiracles homeobox 1
HGNC
NCBI Gene ID
2016
NCBI Gene
HGNC ID
HGNC:3340
HGNC
Ensembl
ENSG00000135638
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q04741Homeobox protein EMX12900Ensembl, GeneID, HGNC

Source UniProt

Patents7

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444927Q04741Espacenet
US 11446398 B22022-09-2027182Q04741Espacenet
JP 2022524081 A2022-04-27130153Q04741Espacenet
US 11078247 B22021-08-033545Q04741Espacenet
JP 2019054813 A2019-04-11225362Q04741Espacenet
JP 2017121241 A2017-07-13225362Q04741Espacenet
JP 2015516143 A2015-06-08225362Q04741Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,074

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEMX1 papersNewest fiscal year
RM1HG009490Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease192025
R35GM118062Integrating Chemistry and Evolution to Illuminate Biology and Enable Novel Therapeutics182025
P30CA014051Cancer Center Support (Core) Grant62025
I01BX000252Chromatin-based regulation of neural stem cells32025
P30EY012196CORE GRANT FOR VISION RESEARCH32025
R01AR063070Skin-targeted Cell Therapy for Recessive Dystrophic Epidermolysis Bullosa32025
UL1TR001863Yale Clinical and Translational Science Award32025
DP2CA281401Scalable Development of Custom Genome Editing Technologies22025
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies22025
P01CA096832NORMAL & NEOPLASTIC GROWTH IN THE BRAIN22025

1 to 10 of 1,074Source NIH's project files

See all 1,074 nih grants

Papers996

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Enhanced CRISPR-Cas3-mediated genome editing using circularized crRNAs.iScience202642741383PubTator, text miningPubMed
Histone demethylase KDM6B promotes postnatal oligodendrocyte maturation and cortical myelination.Front Cell Neurosci202642239646PubTator, text miningPubMed
Ascl1 promotes OPC specification across species and central nervous system regions and its gliogenic function is regulated by phosphorylation.Dev Biol202642191083PubTator, text miningPubMed
MECP2 mutations rewire human ESC fate and bias cortical lineage commitment.Stem Cell Reports202642030940PubTator, text miningPubMed
Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair.Nature202641922774PubTator, text miningPubMed
The landscape and regulatory potential of eccDNAs in mammalian preimplantation embryos.Nat Commun202641917015PubTator, text miningPubMed
Regulated transformation system (RTS): sddi-mediated programmable shut-off and mode switching of base editors.Nucleic Acids Res202641909950PubTator, text miningPubMed
Isogenic cortical organoids enable precision targeting of APP variant-specific pathways in Alzheimer's disease.bioRxiv202641757078PubTator, text miningPubMed
Postnatal conversion of methylcytosine to hydroxymethylcytosine reconfigures the human neuronal epigenome.bioRxiv202641757014PubTator, text miningPubMed
Organoids Gone Viral: A Comprehensive Review on Human Organoid Models to Study Viral Pathogenesis.Viruses202641754581PubTator, text miningPubMed

1 to 10 of 996

See all 996 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2016

GET https://conductscience.org/api/genes/v1/2016/grants?page=2