Gene · 2018
EMX2: empty spiracles homeobox 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EMX2: empty spiracles homeobox 2. Genes, record 2018. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2018
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q04743 | Homeobox protein EMX2 | 252 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents25
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 44928 | Q04743 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 16707 | Q04743 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 14932 | Q04743 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 16707 | Q04743 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 14932 | Q04743 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 14932 | Q04743 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14771 | Q04743 | Espacenet |
| JP 2024519218 A | 2024-05-09 | 112 | Q04743 | Espacenet |
| KR 1020240005837 A | 2024-01-12 | 69 | Q04743 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 27185 | Q04743 | Espacenet |
1 to 10 of 25
See all 25 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants862
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EMX2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| R24HD000836 | Laboratory of Developmental Biology | 3 | 2025 |
| R37NS035129 | Human Epilepsy Genetics - Mosaic Mutations in Focal Epilepsy | 3 | 2025 |
| UL1TR001881 | UCLA Clinical and Translational Science Institute | 3 | 2025 |
| P01CA096832 | NORMAL & NEOPLASTIC GROWTH IN THE BRAIN | 2 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 2 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 2 | 2025 |
| R01CA098571 | Molecular Mechanisms of eIF4E Mediated Transformation | 2 | 2025 |
| R01CA159859 | Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 Medulloblastoma | 2 | 2025 |
| R01DC015242 | Hair Cell Polarization and Sensory Bundle Development | 2 | 2025 |
1 to 10 of 862Source NIH's project files
See all 862 nih grantsPapers900
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Functional convergence of regulatory regions provides vital insights into mammalian gliding adaptation. | Sci China Life Sci | 2026 | 42714797 | PubTator, text mining | PubMed |
| Terminal 4q duplication and extended 10q deletion in a preterm infant with linear growth restriction: transcriptomic evidence of disrupted developmental and metabolic pathways. | Front Pediatr | 2026 | 42395604 | PubTator, text mining | PubMed |
| Establishing Area-Specific Brain Organoids Through Transcription Factor-Mediated Patterning. | Biology (Basel) | 2026 | 41892247 | PubTator, text mining | PubMed |
| Exploring roles of neuroglobin in oxygen homeostasis and neurodevelopment based on human cerebral organoid models. | iScience | 2026 | 41797899 | PubTator, text mining | PubMed |
| De novo rare EMX2 variants lead to idiopathic hypogonadotropic hypogonadism. | Genet Med | 2026 | 41765865 | PubTator, text mining | PubMed |
| Functional Validation of a Novel <italic>PBX1</italic> Missense Variant in a 46,XY Girl. | Sex Dev | 2026 | 41746858 | PubTator, text mining | PubMed |
| An in vivo and in vitro spatiotemporal profile of human midbrain development. | Nat Commun | 2026 | 41633979 | PubTator, text mining | PubMed |
| A developmentally regulated long-range enhancer-promoter contact mediates human neural development. | bioRxiv | 2026 | 41573925 | PubTator, text mining | PubMed |
| Abnormal PLK2 expression is associated with specific subtypes and may help risk stratification in acute myeloid leukemia. | Discov Oncol | 2026 | 41530586 | PubTator, text mining | PubMed |
| Missense variants in homeobox domain of PBX1 cause coracoclavicular ankylosis. | Eur J Hum Genet | 2026 | 41162587 | PubTator, text mining | PubMed |
1 to 10 of 900
See all 900 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2018
GET https://conductscience.org/api/genes/v1/2018/patents?page=2