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ENO1: enolase 1

1 protein, 160 patents, 0 drugs, 0 trials, 4,973 NIH grants and 14,516 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolENO1HGNC
Nameenolase 1HGNC
NCBI Gene ID2023NCBI Gene
HGNC IDHGNC:3350HGNC
EnsemblENSG00000074800NCBI Gene
AliasesENO1-IT1, ENO1L1, HEL-S-17, MBP-1, MPB1, NNE, PPHNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P06733Alpha-enolase4348Ensembl, GeneID, HGNCUniProt

Patents 160

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026022479 A12026-01-292P06733Espacenet
JP 2026004568 A2026-01-1445026P06733Espacenet
EP 4650780 A22025-11-19891P06733Espacenet
EP 4641202 A22025-10-294390P06733Espacenet
JP 2025147176 A2025-10-0614935P06733Espacenet
JP 2025517970 A2025-06-12891P06733Espacenet
JP 2025508740 A2025-04-10237P06733Espacenet
JP 2025028160 A2025-02-2814935P06733Espacenet
KR 1020250017231 A2025-02-044390P06733Espacenet
KR 1020250010750 A2025-01-2114935P06733Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4973

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant272,025NIH's project files
P30CA008748Cancer Center Support Grant162,025NIH's project files
P30EY010572Ophthalmology Core Facility132,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant92,025NIH's project files
P30CA068485Cancer Center Support Grant72,025NIH's project files
P50CA127001SPORE in Brain Cancer72,025NIH's project files
R01CA051497Defining the Role of the Cancer Circadian Clock in Tumor Immunity and Tumorigenesis72,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award72,025NIH's project files
P30CA013148Comprehensive Cancer Center Support Grant62,025NIH's project files
P30CA015704Cancer Center Support Grant62,025NIH's project files

Papers 14516

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826207PubTator, text miningPubMed
42822682PubTator, text miningPubMed
42801660PubTator, text miningPubMed
42782756PubTator, text miningPubMed
42760665PubTator, text miningPubMed
42750204PubTator, text miningPubMed
42750201PubTator, text miningPubMed
42747343PubTator, text miningPubMed
42737562PubTator, text miningPubMed
42733578PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license