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ENPEP: glutamyl aminopeptidase

1 protein, 32 patents, 2 drugs, 15 trials, 3,707 NIH grants and 5,876 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolENPEPHGNC
Nameglutamyl aminopeptidaseHGNC
NCBI Gene ID2028NCBI Gene
HGNC IDHGNC:3355HGNC
EnsemblENSG00000138792NCBI Gene
AliasesAPA, CD249, gp160NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q07075Glutamyl aminopeptidase9577Ensembl, GeneID, HGNCUniProt

Patents 32

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447852Q07075Espacenet
EP 4650780 A22025-11-192448Q07075Espacenet
EP 4641201 A22025-10-292033Q07075Espacenet
JP 2025529142 A2025-09-041394Q07075Espacenet
US 12371689 B22025-07-291394Q07075Espacenet
JP 2025517969 A2025-06-122033Q07075Espacenet
JP 2025517970 A2025-06-122448Q07075Espacenet
EP 4549941 A12025-05-0713Q07075Espacenet
WO 2024004523 A2024-01-0413Q07075Espacenet
JP 2023116581 A2023-08-22108Q07075Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
FIRIBASTATCHEMBL4297511Aminopeptidase A inhibitorINHIBITORChEMBL
TOSEDOSTATCHEMBL2103847Aminopeptidase inhibitorINHIBITORChEMBL

Trials 15

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT04857840FIRIBASTATPHASE3ClinicalTrials.gov
NCT04277884FIRIBASTATPHASE3ClinicalTrials.gov
NCT03198793FIRIBASTATPHASE2ClinicalTrials.gov
NCT02780180FIRIBASTATPHASE2ClinicalTrials.gov
NCT02452346TOSEDOSTATPHASE22018-06-12ClinicalTrials.gov
NCT02352831TOSEDOSTATPHASE1/PHASE22018-12-17ClinicalTrials.gov
NCT02322450FIRIBASTATPHASE2ClinicalTrials.gov
NCT01900184FIRIBASTATPHASE1ClinicalTrials.gov
NCT01636609TOSEDOSTATPHASE1ClinicalTrials.gov
NCT01567059TOSEDOSTATPHASE2ClinicalTrials.gov

NIH grants 3707

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30AI064518Center for AIDS Research382,025NIH's project files
P30AI027767UAB Center for AIDS Research (CFAR)362,025NIH's project files
P30AI027757University of Washington/Fred Hutch Center for AIDS Research262,025NIH's project files
P30AI060354Harvard University Center for AIDS Research252,025NIH's project files
UM1AI068635SDMC: HIV Vaccine Trials Network252,025NIH's project files
P30AI045008Penn Center for AIDS Research222,025NIH's project files
P51OD011132Emory National Primate Research Center222,025NIH's project files
UM1AI068618HIV Vaccine Trials Network Laboratory Center222,025NIH's project files
P30AI050409Center for AIDS Research at Emory University202,025NIH's project files
UM1AI068614HIV Vaccines Clinical Trials Network Leadership and Operations Center192,025NIH's project files

Papers 5876

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42799454PubTator, text miningPubMed
42795832PubTator, text miningPubMed
42736695PubTator, text miningPubMed
42694067PubTator, text miningPubMed
42677561PubTator, text miningPubMed
42592649PubTator, text miningPubMed
42570664PubTator, text miningPubMed
42522626PubTator, text miningPubMed
42509224PubTator, text miningPubMed
42459868PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license